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Severe Combined Immunodeficiency (SCID). What is SCID? Severe Combined Immunodeficiency, otherwise known as SCID. SCID is a group of very rare-and potentially.

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Presentation on theme: "Severe Combined Immunodeficiency (SCID). What is SCID? Severe Combined Immunodeficiency, otherwise known as SCID. SCID is a group of very rare-and potentially."— Presentation transcript:

1 Severe Combined Immunodeficiency (SCID)

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3 What is SCID? Severe Combined Immunodeficiency, otherwise known as SCID. SCID is a group of very rare-and potentially fatal-inherited disorders related to the immune system. SCID makes those affected highly susceptible to life-threatening infections by viruses, bacteria and fungi.

4 What is SCID? Severe Combined Immunodeficiency, otherwise known as SCID. SCID is a group of very rare-and potentially fatal-inherited disorders related to the immune system. SCID makes those affected highly susceptible to life-threatening infections by viruses, bacteria and fungi.

5 Is SCID Inherited?

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7 Chromosome Location? There are several types of SCID. The most common form is caused by a mutation in the SCIDX1 gene located on the X chromosome.

8 Chromosome Location? There are several types of SCID. The most common form is caused by a mutation in the SCIDX1 gene located on the X chromosome.

9 Interesting Facts! One form of SCID became the first human illness treated by human gene therapy in 1990. About 1 out of every 100,000 babies is born with SCID. SCID is sometimes called Bubble Boy disease. In the 1970s, a boy named David Vetter had to live in a plastic bubble for 12 years because of SCID.

10 Interesting Facts! One form of SCID became the first human illness treated by human gene therapy in 1990. About 1 out of every 100,000 babies is born with SCID. SCID is sometimes called Bubble Boy disease. In the 1970s, a boy named David Vetter had to live in a plastic bubble for 12 years because of SCID.

11 Citations http://www.genome.gov/13014325 http://learn.genetics.utah.edu/content/disorders/w hataregd/scid/ http://learn.genetics.utah.edu/content/disorders/w hataregd/scid/ IMAGES http://kidshealth.org/PageManager.jsp?dn=girlshea lth&lic=175&cat_id=132&article_set=21836 http://kidshealth.org/PageManager.jsp?dn=girlshea lth&lic=175&cat_id=132&article_set=21836 US national library of Health


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