1. Rebecca Buchwald

2.  Malaria is a mosquito-borne disease caused by the parasite Plasmodium falciparum.  It is a serious and sometimes fatal disease

3.  Transmitted to humans by female Anopheles mosquitoes.  The mosquitoes are infected by parasites they then pass this disease into humans when they bite and feed.

4.  Grows and replicates in the liver first  Later it infects the red blood cells  Once in the red blood cells, the parasite grows releases daughter cells and then kills the red blood cell  The daughter cells then effect other red blood cells

5.  There are there are two different types of malaria, Uncomplicated, and complicated  Uncomplicated  Less sever form  Complicated  Sever form

6. UNCOMPLICATED Symptoms begin to show when then parasites begin to infect RBCS  Fever  Chills  Sweats  Headaches  Nausea and vomiting  Body aches COMPLICATED Symptoms begin to show when then parasites begin to infect RBCS infections are complicated by serious organ failures or abnormalities in the patient's blood or metabolism  Cerebral malaria  with abnormal behavior, impairment of consciousness, seizures, coma, or other neurologic abnormalities  Severe anemia  Acute kidney failure  Any many more

7. DIAGNOSED  depends on the demonstration of parasites in the blood  It is usually found by microscopy.  Rapid and accurate diagnosis TREATED Can be treated by the use of drugs to kill the parasites  depends on many factors including:  disease severity the species of malaria parasite causing the infection and the part of the world in which the infection was acquired.

8.  depends mainly on climatic factors such as temperature, humidity, and rainfall.  transmitted in tropical and subtropical areas  temperatures below 20°C (68°F), Plasmodium falciparum (which causes severe malaria) cannot complete its growth cycle in the Anopheles mosquito, and thus cannot be transmitted

9.  Heridetary blood disease in which the RBCS become denatured and take on a sickle shape.  The irregular shape of the RBC is the factor that inhibits the growth and stops the spread of the parasite. If the parasite cannot grow, it cannot infect other cells and therefore, cannot spread throughout the body.

10.  Question #1  How is malaria transmitted to humans? ▪ Through the bits of a female mosquito infected with the parasite.  Question #2  Where is malaria mostly seen? ▪ In tropical cultures  Question #3  How does Sickle Cell Anemia stop malaria? ▪ The sickle cell shape inhibits the growth and reproduction of the parasite

11.  Sickle cell disease and controlling malaria. (2010).  Retrieved from http://www.bing.com/images/search?q=sickle cell anemia and malaria&view=detail&id=A02AE9419D367CA85C877E CA660BA19B67D2C50B&first=0&FORM=IDFRIR  Malaria. (2010).  Retrieved from http://www.cdc.gov/malaria/references_resources/ind ex.html http://www.cdc.gov/malaria/references_resources/ind ex.html