1. Intracuring; Intrastromal Corneal Application of Dental Flowable Composite Faik Oruçoğlu (Orucov) Istanbul / Turkey ECC 2010 The author do not have any proprietary interest in the products and drugs mentioned in this presentation. Dr. Oruçoğlu (Orucov) hold patents to the Intracuring method for cornea flattening with intrastromal corneal application of dental flowable composite.

2. A dental restorative or dental filling is a dental restorative material used to restore the functional integrity and morphology of missing tooth structure. A dental restorative or dental filling is a dental restorative material used to restore the functional integrity and morphology of missing tooth structure.dental restorative material morphologydental restorative material morphology flowable composites are more frequently applied because of their flowability and easy handling of the applicator since 1996. flowable composites are more frequently applied because of their flowability and easy handling of the applicator since 1996. Flowable restoratives are low viscosity, visible light-cured, radiopaque materials that are indicated for a variety of uses, including direct restorative pit and fissure sealant, repair of indirect composite porcelain and temporary acrylic materials. Flowable restoratives are low viscosity, visible light-cured, radiopaque materials that are indicated for a variety of uses, including direct restorative pit and fissure sealant, repair of indirect composite porcelain and temporary acrylic materials.

3. Flowability allows the material to be injected through small- gage dispensers thus simplifying the placement procedure and amplifying the range of clinical applications. Flowability allows the material to be injected through small- gage dispensers thus simplifying the placement procedure and amplifying the range of clinical applications. The flowable composites can be easily inserted into small cavities and are expected to exhibit better adaptation to the internal cavity wall compared to the conventional restorative composites. The flowable composites can be easily inserted into small cavities and are expected to exhibit better adaptation to the internal cavity wall compared to the conventional restorative composites.

4. We hypothesized that flowable dental composites could be used in the cornea for the same indications as ICRS for flattening the corneal curvature. We hypothesized that flowable dental composites could be used in the cornea for the same indications as ICRS for flattening the corneal curvature. We called this intrastromal polymerization technique ‘intracuring’ procedure. We called this intrastromal polymerization technique ‘intracuring’ procedure. In this study, dental flowable composites were used intrastromally in sheep corneas for the purpose of flattening the anterior corneal curvature. In this study, dental flowable composites were used intrastromally in sheep corneas for the purpose of flattening the anterior corneal curvature. This is the first experimental study of intrastromal polymerization in changing anterior corneal curvature. This is the first experimental study of intrastromal polymerization in changing anterior corneal curvature.

5. Methods In an experimental laboratory set up eight fresh sheep eyes were used for tunnel creation. In an experimental laboratory set up eight fresh sheep eyes were used for tunnel creation. Before the procedure the corneal epithelium was removed with a corneal scraper in all eyes to have consistently smooth corneal surfaces. Before the procedure the corneal epithelium was removed with a corneal scraper in all eyes to have consistently smooth corneal surfaces. Afterward, the eyes were fixed in an interface, positioned, and attached by applying suction energy to the Femtec laser system Afterward, the eyes were fixed in an interface, positioned, and attached by applying suction energy to the Femtec laser system The laser settings were as follows: tunnel depth in 450 µ; inner diameter 6.6 mm; outer diameter 8.8 mm; entry cut length 0,8 mm. The incision was placed at 12 oclock. The laser settings were as follows: tunnel depth in 450 µ; inner diameter 6.6 mm; outer diameter 8.8 mm; entry cut length 0,8 mm. The incision was placed at 12 oclock.

6. After completion of the laser cut, flowable composite was injected slowly through the tunnel incision until complete filling. After completion of the laser cut, flowable composite was injected slowly through the tunnel incision until complete filling. Excessive composite was cleaned from the incision. Excessive composite was cleaned from the incision. Flat plastic material was used for pressure on the cornea during polymerization. An LED light was applied for polymerization for 20 seconds. Flat plastic material was used for pressure on the cornea during polymerization. An LED light was applied for polymerization for 20 seconds.

8. Results The change on the cornea curvature was observed in the all cadaveric sheep eyes after intracuring intrastromal polymerization. The change on the cornea curvature was observed in the all cadaveric sheep eyes after intracuring intrastromal polymerization. Scheimpflug images showed significant changes on the corneal curvature. Scheimpflug images showed significant changes on the corneal curvature. Therefore, as sheep corneas are flat, more flattening was achieved by the intrastromal polymerization of flowable composites. Therefore, as sheep corneas are flat, more flattening was achieved by the intrastromal polymerization of flowable composites. Flattening in the inferior cornea and steepening at the opposite part was seen on the sagittal curvature map Flattening in the inferior cornea and steepening at the opposite part was seen on the sagittal curvature map

12. Conclusion This new application may be a promising technique for the treatment of keratoconus or myopia. This new application may be a promising technique for the treatment of keratoconus or myopia. The application of this technique in humans could offer improved treatment options in the future The application of this technique in humans could offer improved treatment options in the future The clinical applications and safety of these materials in human corneas require further study. The clinical applications and safety of these materials in human corneas require further study.