1. Barrett’s Esophagus Nutritional Science Period ¾ Mr. Crull Kelly Chen, Razia Begum, Haesol Jun, Nabila Anwara

2. What is an esophagus? Digestive system  a muscular tube that carries food and liquids from the mouth to the stomach using the process of peristalsis  a normal esophagus is lined with a pinkish-white mucous membrane

3. What is Barrett’s Esophagus  color and composition of the cells lining the esophagus change because of repeated exposure to stomach acid  the normal pinkish-white mucus membrane is replaced by an abnormal red membrane(similar to the normal membrane found in the stomach) Barrett’s Esophagus Normal Esophagus

4. continued …What is it?  is a serious form of GERD (gastroesophageal reflux disease)  the regurgitation of acid from your stomach into your esophagus

5. Symptoms…  Heartburn  Ulcers  Burning sensation in the back of the throat  Narrowing of the esophagus that comes from scarring.  Having trouble swallowing.  Vomiting blood/bleeding.

6. Commonly Found In…  adults (1% of adults in the United States have it)  found three times more often in males than in females  middle-aged or elderly Caucasian men are affected more frequently  found less in minority populations  is uncommon in children

7. Deal with it…  No medications to reverse condition, but can slow the progression  Avoid smoking and tobacco products(Nicotine in the blood weakens Lower Esophageal Sphincter)  Avoid fatty foods, caffeine, citrus fruits, spices, & alcohol  Elevate the head of the bed or mattress 6 to 8 inches. (helps to keep acid in the stomach)

8. Why is it so Dangerous?  Increased risk of developing esophageal cancer  Can lead to:  Dysplasia (precancerous changes)  From none to serious changes  Invasive Cancer  Can attack lymph nodes from esophagus

9. How can Barrett’s Esophagus be treated?  Controlling GERD/B.E by:  Avoid foods that cause heartburn  Stop smoking etc.  Proton Pump Inhibitors (PPIs)  Block production of acids  Photodynamic Therapy (PDT)  Use of Photofrin to detect Barrett’s tissue and remove them by laser surgery

10. Bibliography  http://www.mayoclinic.com/health/barretts- esophagus/HQ00312 http://www.mayoclinic.com/health/barretts- esophagus/HQ00312  http://digestive.niddk.nih.gov/ddiseases/pubs /barretts/ http://digestive.niddk.nih.gov/ddiseases/pubs /barretts/  http://www.gicare.com/diseases/Barrett- esophagus.aspx http://www.gicare.com/diseases/Barrett- esophagus.aspx