1. Emphysema Salwa Mukadam TPJ3M0 Miss. Tran A Respiratory Disease

2. Historical Background Comes from the Greek Word: Inflation Emphysan meaning inflate Physa meaning breath, blast Believed to be in existence from the 17 th century by Sir John Floyer Emphysema is described as large air spaces in humans; have trouble exhaling It has been in existence ever since cigars were introduced

3. How it Works... Triggered by inhaled irritants and causes inflammations of the alveoli This causes a loss of elasticity of the lung due to the destruction of Elastin Elastin: An important structural protein in the lung’s supporting connective tissue Alveoli: Small air sacs in the lungs which exchange Oxygen and Carbon dioxide Destroyed Elastin causes a loss of support of the airways, narrowing of the airways, and progressive airflow limitation The enlarged lungs not only make it harder to breathe, but they also lack protection against further damage because much of the Elastin has been destroyed

4. Air is trapped in the Alveoli The Alveoli looses its elasticity thus, making it harder to exhale out

5. Symptoms Shortness of breath Wheezying Chest tightness Reduced capacity for physical activity Chronic coughing Loss of appetite Fatigue

6. Causes Smoking: Most common cause. Chemical irritants slowly destroy the small airways, elastic air sacs and their supporting elastic fibers Protein Deficiency: 1-2% of people with Emphysema have inherited deficiency of a protin called AAT; which protects elastic structure of lungs The progression and serverity are greatly acclerated by smoking

7. Scenario Julie works near a chemical plant and smokes regularly for about 10 years now. She does not exercise and finds her self fatigued after a day of work. She experiences shortness of breath when performing minor activities and she barely eats. Does Julie have Emphysema?

9. Treatments Emphysema is irreversible and permanent Smoking Cessation: Quit smoking immediately to prevent furthur damage - Take medicine such as, Nicorette gum. Do exercises that strengthen the diaphragm:Yoga Clean airways: mucus starts to build up

10. Prevention Best way to prevent emphysema is to NOT smoke Avoid second-hand smoke Wear masks from dust, chemical fumes Exercise regularly to increase lung capacity Nutrition: Take vitamins particularly A, B and Iron- Doctors say Emphysema depletes the body of vitamin A and B

11. Bibliography http://www.lung.ca/diseases-maladies/a-z/emphysema- emphyseme/index_e.php http://www.lung.ca/diseases-maladies/a-z/emphysema- emphyseme/index_e.php http://www.emedicinehealth.com/emphysema/article_e m.htm http://www.emedicinehealth.com/emphysema/article_e m.htm http://www.nlm.nih.gov/medlineplus/emphysema.html http://www.lung.ca/children/grades7_12/lung_health/ emphysema.html http://www.lung.ca/children/grades7_12/lung_health/ emphysema.html