1. Breast Pathology

2. Breast pathology Inflammatory Disorders Acute Mastitis Preiductal Mastitis Mammary Duct Ectasia Fat Necrosis Lymphocytic Mastopathy Granulomatous Mastitis Benign Epth. Lesion Non- proliferative breast changes proliferative breast changes without atypia proliferative breast changes with atypia Carcinoma of the breast

3. The normal microscopic appearance of female breast tissue is shown here. There is a larger duct to the right and lobules to the left. A collagenous stroma extends between the structures. A variable amount of adipose tissue can be admixed with these elements.

4. Here is the microscopic appearance of a fibroadenoma. To the right is compressed breast connective tissue forming a "capsule" to this mass. The neoplasm itself is composed of a fibroblastic stroma in which are located elongated compressed ducts lined by benign appearing epithelium.

5. fibrocystic changes in breast

6. Blue dome cyst

7. Apocrine change

8. epithelial hyperplasia

9. intraductal papilloma

10. Paget's disease

11. Breast Cancer

12. Classification Breast CA

13. Lobular CIS (low)

14. Lobular CIS (high)

15. intraductal carcinoma

16. The cells in the center of the ducts with comedocarcinoma are often necrotic and calcify, as shown here. This central necrosis leads to the gross characteristic of extrusion of cheesy material from the ducts with pressure (comedone-like).

17. Both intraductal and infiltrating ductal carcinoma

18. infiltrating ductal carcinoma

19. colloid, or mucinous carcinoma

20. Invasive lobular carcinoma

22. Medullary carcinomas