1. The National Vaccine Plan Process - Update October 22, 2007 Raymond A. Strikas, MD National Vaccine Program Office Department of Health and Human Services

2. Planning Process Summary Process to date –March 20 and June 5, 2007 interagency meetings –Discussions with Assistant Secretary for Health One-on-one discussions with agencies, Departments: CDC, FDA, NIH, HRSA, AHRQ, ASPR, USAID, DoD Priorities’ development by agencies, Departments

3. Four Categories (1994 Plan’s Goals) Develop new and improved vaccines Ensure optimal safety and effectiveness of vaccines and immunization Better educate the public and members of the health professions on the benefits and risks of immunizations Achieve better use of existing vaccines to prevent disease, disability, and death

4. Top Ten Priority Areas (really 11) 1.Vaccine research and development: Enhance 2.Adult Immunization: Improve immunization rates for vaccines recommended for widespread use among adults to achieve coverage targets 3.Adolescent Immunization: Achieve 90% coverage for ACIP recommended vaccines 4.Barriers to vaccination: Reduce or eliminate financial barriers to access for recommended vaccines for all populations 5.Childhood vaccination: Maintain high coverage 6.New Vaccines: Develop, such as 1.HIV 2.TB 3.Malaria

5. Top Ten Priority Areas (really 11) - continued 7. Vaccine Supply: Enhance security 8. Vaccine Safety: Enhance current infrastructure to better monitor adverse events and determine risk factors and mechanisms for adverse events 9. Compensation: Assure the National Vaccine Injury Program continues to compensate persons truly injured by vaccines 10. Global Health: Advance global disease reduction and eradication goals 11. Surveillance: Assure systems are in place to adequately monitor the epidemiology of vaccine-preventable diseases and immunization coverage

6. Priorities Received from many, but not all, agencies and offices. Limited prioritization within lists offered Few milestones and dates for achievement listed Differences of emphasis to be resolved

7. Our Tasks for the Priorities Review categories, areas, issues in particular –Are all listed appropriate? –What is missing? Propose actions as appropriate (to be completed by lead, contributing agencies) Review proposed lead and contributing agencies To follow: –Prioritization within areas by lead agencies –2012-15 milestones –NVAC review, beginning with Vaccine Supply and Development subcommittee today

8. Stakeholder Involvement Approach Complete priorities’ table Review with National Vaccine Advisory Committee Engage other expert stakeholders through Institute of Medicine expert committee (discussion to follow) Engage broader groups of stakeholders, including the general public –Focus groups’ trial October 30, 2007 –“Deliberation Day” town-hall style meeting(s) to follow