1. DNA Foldable Directions:
Fold 3 pieces of paper, so you have 5 layered flaps
Write “DNA” on the top flap as a title

2. On each flap write: DNA Basics & Organization DNA Structure & Function
DNA Replication
RNA Structure & Function
Comparing DNA & RNA

3. 1. DNA Basics & Organization

4. (Inside) On Top Half of 1st Flap write:
1. Make the following flow chart:
Cell  Nucleus  Chromosome DNA  Gene
2. Glue in the following picture below it
Segment of DNA

5. (Inside) On Bottom Half of 1st Flap write:
DNA stands for “Deoxyribonucleic acid”
(type of organic molecule)
DNA is the instructions for making proteins that carry out life functions

6. 2. DNA Structure & Function

7. (Inside) On Top Half of 2nd Flap write:
Directions:
Write “DNA STRUCTURE”
Cut out panel and glue into flap
Circle the following:
Green= Phospahte Group
Red= Sugar
Blue=Nitrogenous bases
Yellow=Nucleotide
Purple= Sugar-Phosphate backbone
DNA is has a double helical shape!

8. (Inside) On Top Bottom Half of 2nd Flap write:
Directions:
Write “DNA FUNCTION”
Make the following table:
Function:
Facts:
Storage of Genetic Code
double stranded sugar-phosphate backbone
internal code (nitrogenous bases are protected by sugar-phosphate backbone)
coiled tightly to allow for more surface area  meaning more room to store genetic code
Passing of Traits
nitrogen bases are complementary (A or adenine always bonds with T or thymine; C or cytosine always bonds with G or guanine)
weak hydrogen bonds hold bases together- allow for ease during replication

9. 3. DNA Replication

10. (Inside) On Top Half of 3rd Flap write:
Directions:
Cut out panel and glue into flap
Color the following in picture #1:
Green= Parent Strand
Yellow= Complementary Strand
Outline the following: in picture #2:
Red = Leading strand
Blue = Lagging strand #1 #2

11. (Inside) On Top Bottom Half of 3rd Flap write
Leading Strand ONLY!
Write “Steps of DNA Replication”
Make the following flow chart:
3. Elongation DNA protein polymerase reads template strand and continuously adds new nucleotides that are complementary to the parent strand
1. DNA unwinds with help of protein helicase, this breaks weak hydrogen bonds between bases
2. The protein primase attached to the parent strand, this helps bind (attach) new nucleotides
Lagging Strand ONLY!
5. DNA Termination
4. DNA primers are removed & DNA ligase adds sugars and phosphates in gaps made by fragments
3. DNA primase adds more primers, DNA is elongated in short segments (okazzki fragments) by DNA polymerase and then is
6. DNA repairs itself

12. 4. RNA Structure & Function

13. (Inside) On Top Half of 4th Flap write:
Directions:
Write “RNA STRUCTURE”
Cut out pictures, glue into flap and label types of RNA
rRNA
mRNA
tRNA

14. (Inside) On Top Bottom Half of 4th Flap write:
Directions:
Write “RNA FUNCTION”
Make the following table:
Type of RNA:
Function:
mRNA
“messenger”
makes a copy of DNA in the nucleus
travels from nucleus  cytoplasm  ribosome
bases in mRNA are read in sets of 3 = codon
rRNA
“ribosomal”
“home” of protein synthesis= mRNA brings code, tRNA brings amino acids and rRNA puts the two together to make protein
tRNA
“transfer”
gathers amino acids
travels to the ribosome
contains a set of 3 bases in tRNA (anticodon)

15. 5. Comparing DNA & RNA

16. (Inside) On Top Half of 5th Flap write:
Directions:
Cut out panel and glue into flap

17. (Inside) On Bottom Half of 5th Flap:
Directions:
1. Draw & Complete the following Venn Diagram:
DNA
RNA