1. Useable Biomaterials in Dental Implants Stephen Sladen BME 281 Second Presentation BME 281 Second Presentation

2. Dental Implants First known use by Maya civilization (600 AD). 1952 – Dr. Leonard Linkow placed first implant. Known to be the father of modern implant dentistry. 1959 – Stefano Melchiade Tramonte saw titanium screw could support prosthesis. Human trial results (1966). Bone grafts required.

3. Bone Grafting Surgical procedure to replace damaged or unhealthy bone. Patients suffering from periodontal disease. Dental implants needed. Osteoconduction vs. Osteoinduction Graft material sources AutograftAllograft Biomaterials (Metal, Ceramic, Synthetic Polymers, etc.)

4. Fast Response Biomaterial Dr. Cameron Lutton - Inflammatory response polymer. Healing process Structure – attracts/repels proteins.

5. Results Lutton’s preliminary results were successful. Presented to Orthopedic Research Society (2008). Currently animal trials. (Limitation) Begin treatment of patients with bone disease.

6. Future Innovations Titanium foam implants (Fraunhofer Institute for Manufacturing Technology and Advanced Materials Research). Laser cut implants, degradable (Institute for Laser Technology). Closer to biological joint replacement. Bone grafts still remains a competitive market.

7. References Nascimento, C.; Issa, J. P. M.; Oliveira, R. R.; Iyomasa, M. M.; Siessere, S. & Regalo, S. C. H. Biomaterials applied to the bone healing process. Int. J. Morphol., 25(4):839-846, 2007...http://www.abc.net.au/science/articles/2009/02/19/2495828.htm “Innovations in Human-Bone Repair and Replacement.” Evans, Nicola. November2010.. http://www.strategicbusinessinsights.com/abo ut/featured/2010/2010-11-bonerepair.shtmlhttp://www.strategicbusinessinsights.com/abo ut/featured/2010/2010-11-bonerepair.shtml “Bone Grafting”. http://en.wikipedia.org/wiki/Bone_grafting. Complementary & Alternative Medicene Article (photo).. Complementary & Alternative Medicene Article (photo).