1. Green & Sustainable Chemistry
DIPARTIMENTO
SCIENZE CHIMICHE E TECNOLOGIE DEI MATERIALI
Green & Sustainable Chemistry
Luigi Ambrosio
Department of Chemical Science and Materials Technology
National Research Council of Italy
Piazzale A. Moro, Roma

2. SCIENZE CHIMICHE E TECNOLOGIE DEI MATERIALI
DIPARTIMENTO
SCIENZE CHIMICHE E TECNOLOGIE DEI MATERIALI
Network
METODOLOGIE CHIMICHE
ROMA
STUDIO DELLE MACROMOLECOLE
MLANO, MMilano, Genova, Biellae Bi
STUDIO DEI MATERIALI NANOSTRUTTURATi
ROMA, Palermo, Bologna
SINTESI ORGANICA E LA FOTOREATTIVITA'
BOLOGNA e Ferrara
SCIENZE E TECNOLOGIE MOLECOLARI
MILANO, Padova e Perugia
TECNOLOGIA DELLE MEMBRANE
COSENZA e Padova
MATERIALI COMPOSITI E BIOMEDICI
NAPOLI e Pisa
CRISTALLOGRAFIA
BARI e Roma
BIOSTRUTTURE E BIOIMMAGINI
NAPOLI e Catania
CHIMICA INORGANICA E DELLE SUPERFICI
PADOVA
CHIMICA E TECNOLOGIA DEI POLIMERI
CHIMICA DEL RICONOSCIMENTO MOLECOLARE
MILANO e Roma
CHIMICA DEI COMPOSTI ORGANO-METALLICI
FIRENZE, Bari e Pisa
CHIMICA BIOMOLECOLARE
NAPOLI, Sassari, Catania, Roma e Padova
SCIENZE E TECNOLOGIE DEI MATERIALI CERAMICI
FAENZA

3. SCIENZE CHIMICHE E TECNOLOGIE DEI MATERIALI
DIPARTIMENTO
SCIENZE CHIMICHE E TECNOLOGIE DEI MATERIALI
- Biopharmaceutical properties
- Drug delivery
Drug discovery
Biomaterials & Tissue
Engineering
Biosensors
Computational modeling
- New catalysts
- Enzymatic reactions
Hydrogen generation
and storage
Renewable energy sources
Processes with low
environmental risk
- Nanostructures, nanomaterials
- Photonics, optoelectronics
Polymer composites
Materials technologies
Surface technologies
Computational modelling
Sensors
Health
Sustainability
Converging Technologies
Molecular Design for Social and Economic Needs
Pharmaceuticals
Food
Security
Transport
Industrial Processes
Next Manufacturing 3

4. SCIENZE CHIMICHE E TECNOLOGIE DEI MATERIALI
DIPARTIMENTO
SCIENZE CHIMICHE E TECNOLOGIE DEI MATERIALI
PROJECTS/PLATFORMS
1. New molecules with specific biochemical properties
2. Polymer systems for functional and structural properties
3. Novel products and processes for sustainable chemistry
4. Nano-structured systems with electronic properties
5. Molecular based design and modification of coatings
6. Enabling technologies for drug discovery
7. Predictive modeling of functionalities 4

5. The project strategy SUSTAINABLE CHEMISTRY Energy Efficiency
Design and development,
of new synthetic
processes
Improve the existing
(catalytic) processes
Progetto PM-P03 “Innovative products
and processes for
sustainable
chemistry“
SUSTAINABLE
CHEMISTRY
Energy
Efficiency
and selectivity
Valorization of
renewable
resources
STRATEGIC
OBJECTIVES
Environmental
issues
Hydrogen
technology
Alternative fuels
Sustainable
production
of energy
Reuse and
Recycle of waste
materials
Valorization
and abatement
of pollutants
Process
optimization
Biorefinery
Photovoltaic
Conversion of
renewable
feedstock

6. H2 Production H 2 Highlights Red bacteria HYDROLAB Solar energyF
IRENZE
Production H 2
Red bacteria
Solar energy
Highlights
Organic acids
Lacto
bacteria H2
Vegetal wastes
compost
H2 PHOTOBIOLOGICAL PRODUCTION FROM NON SULFUREUS RED BACTERIA FROM VEGETAL WASTES AND SOLAR ENERGY

7. Project Ve.Li.Ca. – Bioraffinary from Linen e Kanapa
Biolubricants
Polyols
ω-3
IBC
IBBA
Genotype
Selection
Hydrolyzed protein
Biomass
ICRM
Oligomers and carbohydrates
Oil
Pressatura
ISTM
Glicerol
ISMAC
Biopolymers
Packaging
Fibres

8. The Twelve Principles of GREEN CHEMISTRY

9. Sustainability: Green Chemistry:
"Meeting the needs of the present without compromising the ability of future generations to meet their needs.“
is the goal
Green Chemistry:
Technologies that are energy efficient, minimise or preferably eliminate the formation of waste, avoid the use of toxic and/or hazardous solvents and reagents and, where possible, utilise renewable, raw, materials.
is the mean

10. SUSTAINABLE CHEMISTRY
Catalysis
Safer Reactions
& Reagents
Solvent
Replacement
Separation
Processes
Sustainable chemistry
Use of
Renewable
Feedstocks
Energy
Efficiency
Waste
Minimisation
Process
Intensification

11. Enhanced global warming Depletion of resources (not only fuels!)
SOCIETAL CHALLANGES
Enhanced global warming
Depletion of resources (not only fuels!)
Food shortages
Shortages of potable water
Population growth - aging
Waste & pollution
FOOD +70% by 2050

12. KEY ENANBLIG TECHNOLOGY
In 2009, European Member States and the European Commission identified Key EnablingTechnologies (KETs) for their potential impact in strengthening Europe's industrial and innovation capacity.
Six KETs
nanotechnology
micro and nanoelectronics
advanced materials
photonics
industrial biotechnology
advanced manufacturing systems

13. THE “VALLEY OF DEATH”
Whilst European R&D is generally strong in new KET technologies, the HLG has observed that the transition from ideas arising from basic research to competitive KETs production is the weakest link in European KET enabled value chains.
The gap between basic knowledge generation and the subsequent commercialization of this knowledge in marketable products, has been commonly identified across the KETs and is known in broad terms as the "valley of death" issue.
This “Valley of Death” has been identified in many competitor countries, including the USA, China and Taiwan. All have established coordinated programmes in strategically important areas that cover the full innovation chain addressing basic and applied research, demonstrators, standardization measures, deployment and market access, all at the same time and, significantly, in a logical joined-up manner.

14. AN INTEGRATED APPROACH TO KETS FOR FUTURE
COMPETITIVENESS: THREE PILLAR BRIDGE MODEL TO PASS ACROSS THE "VALLEY OF DEATH "
The technological research pillar based on technological facilities supported by research technology organisation;
The product development pillar based on pilot lines and demonstrator supported by industrial consortia
The competitive manufacturing pillar based on globally competitive manufacturing facilities supported by anchor companies.

15. Key Enabling Technologies…..
……..multidisciplinary and trans-sectorial, cutting across many technology areas with a trend towards convergence, technology
integration and the potential to induce structural change

16. INDUSTRIAL BIOTECHNOLOGY
“the application of science and technology to living organisms, as well as parts, products and models thereof, to alter living or non-living materials for the production of knowledge, goods and services.”
Main biotechnology techniques :
DNA/RNA.
Proteins and other molecules
Cell and tissue culture and engineering.
Process biotechnology techniques.
Gene and RNA vectors
Bioinformatics
Nanobiotechnology

17. Biological Intermediates substituting petrochemical
Emerging Trend
Biological Intermediates substituting petrochemical
building blocks 17

18. Synthetic biology
very important step forward, since it allows designing chemicals that would not occur by natural pathways.
to obtain “unnatural” products by modifying bacteria (i.e. Escherichia coli) or modifying yeasts opens a wide new field for the production of tailor made chemicals for very different purposes.
Advanced research synthetic biology,
- At present the genetic modification of bacteria allows to obtain for example tailor recombinant polymers (protein, polysaccharides ect.) or foreseen applications as elimination of toxic residues ect. 18

19. ………still limitation in process sustainability - Sources
Energy balance in different processing steps
Environmental impact in the processing steps (chemicals, etc)
Economic balance
Product stability
Interfaces
Regulation
Ethical Issue
To overcome the limitation of actual process sustainability
Knowledge and new tools from Chemistry , Synthetic biology and Nanotechnology 19

20. SCIENZE CHIMICHE E TECNOLOGIE DEI MATERIALI
DIPARTIMENTO
SCIENZE CHIMICHE E TECNOLOGIE DEI MATERIALI
………Fully exploit the scope of relevant R&D definitions in its programmes which support the full and simultaneous implementation the innovation chain, from basic research, through technological research, product development and prototyping up to globally competitive manufacturing.

21. THANK YOU FOR YOUR KIND ATTENTION !
DIPARTIMENTO
SCIENZE CHIMICHE E TECNOLOGIE DEI MATERIALI
THANK YOU FOR YOUR KIND ATTENTION !