1. Epi Team Challenge Detectives in the Classroom - Investigation 2-7: Epi Team Challenge Epi Team Challenge

2. 1 How is this disease distributed? Hypotheses 3 Is the association causal? 4 What should be done to prevent the disease? 5 Did the prevention strategy work? Where are we and where are we going? What’s my hypothesis? 2 Is there an association? Did the exposure and the disease turn up together? Detectives in the Classroom - Investigation 2-7: Epi Team Challenge

3. Time ++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ Healthy People - E Random Assignment E DZ Controlled Trial Time ++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ Healthy People - E E DZ Cohort Study Time ++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ - DZ E E E E Case-Control Study Time ++++++++++++++++++++++++++++++++++++++++++++++++++++++++++ - E E DZ Cross-Sectional Study DZ What’s My Design? Detectives in the Classroom - Investigation 2-7: Epi Team Challenge

4. Epidemiologist is involved during the entire time from exposure to disease. Assign treatment and control groups. Follow through time and compare risk of disease in treatment group with risk of disease in control group. Give exposure to treatment group, but not control group. What’s My Design? Detectives in the Classroom - Investigation 2-7: Epi Team Challenge Practice Clue Trial

5. Assign treatment and control groups. What’s My Design? Detectives in the Classroom - Investigation 2-7: Epi Team Challenge Clue 1 Begin Epi Team Challenge Trial

6. Observational Study Flow Diagram DZ - E E E E Clue 2 Case-Control Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

7. Observational Study Flow Diagram Clue 3 What’s My Design? Detectives in the Classroom - Investigation 2-7: Epi Team Challenge Cohort, Case-Control, and Cross-Sectional Studies

8. Follow through time and compare risk of disease in exposed group with risk of disease in the unexposed group. Clue 4 Trial and Cohort Study What’s My Design? Detectives in the Classroom - Investigation 2-7: Epi Team Challenge

9. Follow through time and compare risk of disease in treatment group with risk of disease in control group. Give exposure to treatment group, but not control group. Clue 5 Trial What’s My Design? Detectives in the Classroom - Investigation 2-7: Epi Team Challenge

10. Epidemiologist is involved during the entire time from exposure to disease. Clue 6 Trial and Cohort Study What’s My Design? Detectives in the Classroom - Investigation 2-7: Epi Team Challenge

11. Select a group of people with disease and a similar group of people without disease. Clue 7 Case-Control Study What’s My Design? Detectives in the Classroom - Investigation 2-7: Epi Team Challenge

12. Healthy People Flow Diagram - Healthy People E E Random Assignment Non-Observational Study Clue 8 Trial What’s My Design? Detectives in the Classroom - Investigation 2-7: Epi Team Challenge

13. Observational Study Flow Diagram E E - DZ Clue 9 Cross Sectional Study What’s My Design? Detectives in the Classroom - Investigation 2-7: Epi Team Challenge

14. Compare percent of exposed people in the two groups. Clue 10 Case-Control Study What’s My Design? Detectives in the Classroom - Investigation 2-7: Epi Team Challenge

15. Healthy People Flow Diagram - Healthy People E E DZ Random Assignment Clue 11 Trial What’s My Design? Detectives in the Classroom - Investigation 2-7: Epi Team Challenge

16. Flow Diagram Clue 12 Cross Sectional Study What’s My Design? Detectives in the Classroom - Investigation 2-7: Epi Team Challenge

17. Flow Diagram DZ Observational Study Clue 13 Cohort Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

18. Ask each person about both exposure and disease at that point in time. What’s My Design? Clue 14 Cross Sectional Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge

19. Ask both groups about their exposures in the past. What’s My Design? Clue 15 Case-Control Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge

20. Healthy People Flow Diagram - Healthy People Random Assignment Clue 16 Trial Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

21. Disease risk in exposed group is compared to disease risk in unexposed group. Clue 17 Trial, Cohort Study, and Cross Sectional Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

22. Flow Diagram E E - DZ Clue 18 Cross Sectional Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

23. Select a healthy study sample. Clue 19 Trial (?) and Cohort Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

24. Observe who has and has not been exposed. Clue 20 Cohort and Cross-Sectional Studies Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

25. Clue 21 Give exposure to treatment group, but not control group. Trial Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

26. Healthy People Flow Diagram - Healthy People E E Observational Study Clue 22 Cohort Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

27. Epidemiologist is involved after disease has occurred and relies on subjects’ memories to gather information about exposure. Clue 23 Case-Control Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

28. Select a study sample. Clue 24 Trial, Cohort, Case-Control, and Cross Sectional Studies Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

29. Healthy People Flow Diagram - Healthy People E E DZ Observational Study Clue 25 Cohort Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

30. Epidemiologist gathers data only at that one point in time. Clue 26 Cross Sectional Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

31. Flow Diagram DZ Clue 27 Trial and Cohort Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

32. Follow through time and compare risk of disease in exposed group to risk of disease in unexposed group. Clue 28 Trial and Cohort Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

33. Epidemiologist is involved during the entire time from exposure to disease. Clue 29 Trial and Cohort Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

34. Flow Diagram E E DZ Clue 30 Cross Sectional Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

35. Flow Diagram DZ - Clue 31 Case-Control Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

36. Ask each person about both exposure and disease at that point in time. Epidemiologist gathers data only at that one point in time. Disease risk in exposed group is compared to disease risk in unexposed group. Select a study sample. Clue 32 Cross Sectional Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

37. Epidemiologist is involved after disease has occurred and relies on subjects’ memories to gather information about exposure. Select a group of people with disease and a similar group of people without disease. Compare percent of exposed people in the two groups. Ask both groups about their exposures in the past. Case-Control Study Clue 33 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

38. Epidemiologist is involved during the entire time from exposure to disease. Select a healthy study sample. Follow through time and compare risk of disease in exposed group to risk of disease in unexposed group. Observe who has and has not been exposed. Cohort Study Clue 34 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

39. Epidemiologist is involved during the entire time from exposure to disease. Assign treatment and control groups. Follow through time and compare risk of disease in treatment group with risk of disease in control group. Give exposure to treatment group, but not control group. Trial Clue 35 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

40. End Epi Team Challenge Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

41. Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

42. Detectives in the Classroom Name: ________________________ Investigation 2-7: Epi Log Worksheet Date: _____/_____/_____ Circle the study design(s) that is described or depicted by each clue. Some clues describe more than one design. Assign participants to treatment and control groups. Cross-SectionalCase-ControlCohort Trial 1. Clue Study Designs Practice Clue 1 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

43. 1.TrialCohortCase-ControlCross-Sectional 2.TrialCohortCase-ControlCross-Sectional Ask both groups about their exposures in the past. Clue Study Designs Detectives in the Classroom Name: ________________________ Investigation 2-7: Epi Log Worksheet Date: _____/_____/_____ Circle the study design(s) that is described or depicted by each clue. Some clues describe more than one design. Practice Clue 2 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

44. 1.TrialCohortCase-ControlCross-Sectional 2.TrialCohortCase-ControlCross-Sectional 3.TrialCohortCase-ControlCross-Sectional Ask each person about both exposure and disease at that point in time. Clue Study Designs Detectives in the Classroom Name: ________________________ Investigation 2-7: Epi Log Worksheet Date: _____/_____/_____ Circle the study design(s) that is described or depicted by each clue. Some clues describe more than one design. Practice Clue 3 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

45. 1.TrialCohortCase-ControlCross-Sectional 2.TrialCohortCase-ControlCross-Sectional 3.TrialCohortCase-ControlCross-Sectional 4.TrialCohortCase-ControlCross-Sectional Epidemiologist is involved during the entire time from exposure to disease. Practice Clue 4 Clue Study Designs Detectives in the Classroom Name: ________________________ Investigation 2-7: Epi Log Worksheet Date: _____/_____/_____ Circle the study design(s) that is described or depicted by each clue. Some clues describe more than one design. Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

46. Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

47. Assign treatment and control groups. Clue 1 Begin Assessment Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

48. Observational Study Flow Diagram DZ - E E E E Clue 2 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

49. Flow Diagram Observational Study Clue 3 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

50. Follow through time and compare risk of disease in treatment group with risk of disease in control group. Clue 4 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

51. Select a group of people with disease and a similar group of people without disease. Clue 5 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

52. Healthy People Flow Diagram - Healthy People E E Random Assignment Non-Observational Study Clue 6 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

53. Observational Study Flow Diagram E E - DZ Clue 7 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

54. Compare percent of exposed people in the two groups. Clue 8 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

55. Healthy People Flow Diagram - Healthy People E E DZ Random Assignment Non-Observational Study Clue 9 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

56. Flow Diagram Clue 10 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

57. Flow Diagram DZ Observational Study Clue 11 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

58. Ask each person about both exposure and disease at that point in time. Clue 12 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

59. Ask both groups about their exposures in the past. Clue 13 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

60. Healthy People Flow Diagram - Healthy People Random Assignment Clue 14 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

61. Disease risk in exposed group is compared to disease risk in unexposed group. Clue 15 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

62. Flow Diagram E E - DZ Clue 16 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

63. Observe who has and has not been exposed. Clue 17 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

64. Clue 18 Give exposure to treatment group, but not control group. Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

65. Healthy People Flow Diagram - Healthy People E E Clue 19 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

66. Epidemiologist is involved after disease has occurred and relies on subjects’ memories to gather information about exposure. Clue 20 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

67. Select a study sample. Clue 21 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

68. Epidemiologist gathers data only at that one point in time. Clue 22 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

69. Flow Diagram DZ Clue 23 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

70. Epidemiologist is involved during the entire time from exposure to disease. Clue 24 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

71. Flow Diagram E E DZ Clue 25 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

72. Flow Diagram DZ - Clue 26 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

73. Ask each person about both exposure and disease at that point in time. Epidemiologist gathers data only at that one point in time. Disease risk in exposed group is compared to disease risk in unexposed group. Select a study sample. Clue 27 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

74. Epidemiologist is involved after disease has occurred and relies on subjects’ memories to gather information about exposure. Select a group of people with disease and a similar group of people without disease. Compare percent of exposed people in the two groups. Ask both groups about their exposures in the past. Clue 28 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

75. Epidemiologist is involved during the entire time from exposure to disease. Select a healthy study sample. Follow through time and compare risk of disease in exposed group to risk of disease in unexposed group. Observe who has and has not been exposed. Clue 29 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

76. Epidemiologist is involved during the entire time from exposure to disease. Assign treatment and control groups. Follow through time and compare risk of disease in treatment group with risk of disease in control group. Give exposure to treatment group, but not control group. Clue 30 End Assessment Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

77. Could I identify the different study designs? Could I accurately describe the different study designs to someone else? Could I identify a single characteristic of a study design that distinguishes it from the other designs? Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

78. Assign treatment and control groups. Clue 1 Trial Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

79. Observational Study Flow Diagram DZ - E E E E Clue 2 Case-Control Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

80. Flow Diagram Observational Study Clue 3 Cohort, Case-Control, and Cross Sectional Studies Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

81. Follow through time and compare risk of disease in treatment group with risk of disease in control group. Clue 4 Trial and Cohort Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

82. Select a group of people with disease and a similar group of people without disease. Clue 5 Case-Control Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

83. Healthy People Flow Diagram - Healthy People E E Random Assignment Non-Observational Study Clue 6 Trial Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

84. Observational Study Flow Diagram E E - DZ Clue 7 Cross Sectional Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

85. Compare percent of exposed people in the two groups. Clue 8 Case-Control Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

86. Healthy People Flow Diagram - Healthy People E E DZ Random Assignment Non-Observational Study Clue 9 Trial Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

87. Flow Diagram Clue 10 Cross Sectional Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

88. Observational Study Flow Diagram DZ Clue 11 Cohort Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

89. Ask each person about both exposure and disease at that point in time. Clue 12 Cross Sectional Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

90. Ask both groups about their exposures in the past. Clue 13 Case-Control Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

91. Healthy People Flow Diagram - Healthy People Random Assignment Clue 14 Trial Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

92. Disease risk in exposed group is compared to disease risk in unexposed group. Clue 15 Trial, Cohort Study, and Cross Sectional Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

93. Flow Diagram E E - DZ Clue 16 Cross Sectional Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

94. Observe who has and has not been exposed. Clue 17 Cohort Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

95. Clue 18 Give exposure to treatment group, but not control group. Trial Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

96. Healthy People Flow Diagram - Healthy People E E Clue 19 Cohort Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

97. Epidemiologist is involved after disease has occurred and relies on subjects’ memories to gather information about exposure. Clue 20 Case-Control Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

98. Select a study sample. Clue 21 Trial, Cohort, Case-Control, and Cross Sectional Studies Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

99. Epidemiologist gathers data only at that one point in time. Clue 22 Cross Sectional Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

100. Flow Diagram DZ Clue 23 Trial and Cohort Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

101. Epidemiologist is involved during the entire time from exposure to disease. Clue 24 Trial and Cohort Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

102. Flow Diagram E E DZ Clue 25 Cross Sectional Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

103. Flow Diagram DZ - Clue 26 Case-Control Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

104. Ask each person about both exposure and disease at that point in time. Epidemiologist gathers data only at that one point in time. Disease risk in exposed group is compared to disease risk in unexposed group. Select a study sample. Clue 27 Cross Sectional Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

105. Epidemiologist is involved after disease has occurred and relies on subjects’ memories to gather information about exposure. Select a group of people with disease and a similar group of people without disease. Compare percent of exposed people in the two groups. Ask both groups about their exposures in the past. Clue 28 Case-Control Study Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

106. Epidemiologist is involved during the entire time from exposure to disease. Select a healthy study sample. Follow through time and compare risk of disease in exposed group to risk of disease in unexposed group. Observe who has and has not been exposed. Cohort Study Clue 29 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

107. Epidemiologist is involved during the entire time from exposure to disease. Assign treatment and control groups. Follow through time and compare risk of disease in treatment group with risk of disease in control group. Give exposure to treatment group, but not control group. Trial Clue 30 Detectives in the Classroom - Investigation 2-7: Epi Team Challenge What’s My Design?

108. CDC Investigation 2-7 has ended. Epi Team Challenge Detectives in the Classroom - Investigation 2-7: Epi Team Challenge