1. DZ E E d b c a Flow Diagram 2x2 Table Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables & “fit” Designs, Diagrams, and Tables Healthy People - E E DZ

2. 1 How is this disease distributed? Hypotheses 3 Is the association causal? 4 What should be done to prevent the disease? 5 Did the prevention strategy work? Where are we and where are we going? What’s my hypothesis? 2 Is there an association? Did the exposure and the disease turn up together? Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

3. Controlled Trial +++++++++++++++++++++++++++++++++++++++++++++++++++++ +++++++++++++++++++++++++++++++++++++++++++++++++++++ ++ Cohort Study +++++++++++++++++++++++++++++++++++++++++++++++++++++ +++++++++++++++++++++++++++++++++++++++++++++++++++++ + Case-Control Study ++++++++++++++++++++++++++++++++++++++++++++++++++++ E E E E DZ +++++++++++++++++++++++++++ ++++++++++++++++++++++++ +++++++++++++++++++++++++ +++++++++++++++++++++++ Cross-Sectional Study - - - - Review Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

4. Controlled Trial Cohort Study Case-Control Study Cross-Sectional Study Healthy People - E Random Assignment E DZ Healthy People - E E DZ - E E E E - E E Review Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

5. DZ E E d b c a Flow Diagram 2x2 Table & “fit” Designs, Diagrams, and Tables Healthy People - E E DZ Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

6. & Designs, Diagrams, and Tables Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

7. DZ E E a 2x2 Table Where do these people “fit” in the 2x2 table? Flow Diagram Controlled Trial Healthy People E E DZ Random Assignment Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

8. DZ E E b Flow Diagram 2x2 Table Healthy People E E DZ Random Assignment Where do these people “fit” in the 2x2 table? Controlled Trial Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

9. DZ E E c Flow Diagram 2x2 Table Flow Diagram Healthy People E E DZ Random Assignment Where do these people “fit” in the 2x2 table? Controlled Trial Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

10. DZ E E d 2x2 Table Flow Diagram Healthy People E E DZ Random Assignment Where do these people “fit” in the 2x2 table? Controlled Trial Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

11. DZ E E c Flow Diagram 2x2 Table Where are these people in the flow diagram? Cohort Study Healthy People E E DZ Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

12. DZ E E a 2x2 Table Where are these people in the flow diagram? Flow Diagram Cohort Study Healthy People E E DZ Healthy People Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

13. DZ E E d Flow Diagram 2x2 Table Where are these people in the flow diagram? Cohort Study Healthy People E E DZ Healthy People Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

14. DZ E E b Flow Diagram 2x2 Table Where are these people in the flow diagram? Cohort Study Healthy People E E DZ Healthy People Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

15. DZ E E a Where do these people go in the 2x2 table? 2x2 Table Flow Diagram Case-Control Study DZ E E E E Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

16. DZ E E c Where do these people go in the 2x2 table? Flow Diagram 2x2 Table Case-Control Study DZ E E E E Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

17. Flow Diagram DZ E E b 2x2 Table Where do these people go in the 2x2 table? Case-Control Study DZ E E E E Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

18. Flow Diagram DZ E E d 2x2 Table Where do these people go in the 2x2 table? Case-Control Study DZ E E E E Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

19. DZ E E a Flow Diagram 2x2 Table Where do these people go in the 2x2 table? Cross-Sectional Study E E DZ Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

20. DZ E E c Flow Diagram 2x2 Table Where do these people go in the 2x2 table? Cross-Sectional Study E E DZ Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

21. DZ E E d Flow Diagram 2x2 Table Where do these people go in the 2x2 table? Cross-Sectional Study E E DZ Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

22. DZ E E b Flow Diagram 2x2 Table Where do these people go in the 2x2 table? Cross-Sectional Study E E DZ Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

23. Assessment Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

24. DZ E E Flow Diagram 2x2 Table Where do these people “fit” in the 2x2 table? 1. a b c d E E DZ Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

25. DZ E E 2x2 Table Where do these people “fit” in the 2x2 table? Flow Diagram 2. a b c d Flow Diagram Healthy People E E DZ Random Assignment Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

26. DZ E E Where do these people “fit” in the 2x2 table? 2x2 Table Flow Diagram 3. a b c d DZ E E E E Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

27. DZ E E Flow Diagram 2x2 Table Where do these people “fit” in the 2x2 table? 4. a b c d E E DZ Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

28. DZ E E Flow Diagram 2x2 Table Where do these people “fit” in the 2x2 table? 5. a b c d Healthy People E E DZ Random Assignment Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

29. Flow Diagram DZ E E 2x2 Table Where do these people “fit” in the 2x2 table? 6. a b c d DZ E E E E Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

30. DZ E E Flow Diagram 2x2 Table Where do these people “fit” in the 2x2 table? 7. a b c d E E DZ Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

31. DZ E E Flow Diagram 2x2 Table Where do these people “fit” in the 2x2 table? 8. a b c d Healthy People E E DZ Random Assignment Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

32. DZ E E Where do these people “fit” in the 2x2 table? Flow Diagram 2x2 Table 9. a b c d DZ E E E E Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

33. DZ E E Flow Diagram 2x2 Table Where do these people “fit” in the 2x2 table? 10. a b c d E E DZ Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

34. DZ E E a Flow Diagram 2x2 Table Where do these people “fit” in the 2x2 table? 1. (Answer) E E DZ Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

35. DZ E E a 2x2 Table Where do these people “fit” in the 2x2 table? Flow Diagram 2. (Answer) Healthy People E E DZ Random Assignment Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

36. DZ E E a Where do these people “fit” in the 2x2 table? 2x2 Table Flow Diagram 3. (Answer) DZ E E E E Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

37. DZ E E b Flow Diagram 2x2 Table Where do these people “fit” in the 2x2 table? 4. (Answer) E E DZ Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

38. DZ E E b Flow Diagram 2x2 Table Where do these people “fit” in the 2x2 table? 5. (Answer) Healthy People E E DZ Random Assignment Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

39. Flow Diagram DZ E E b 2x2 Table Where do these people “fit” in the 2x2 table? 6. (Answer) DZ E E E E Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

40. DZ E E c Flow Diagram 2x2 Table Where do these people “fit” in the 2x2 table? 7. (Answer) E E DZ Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

41. DZ E E c Flow Diagram 2x2 Table Where do these people “fit” in the 2x2 table? 8. (Answer) Healthy People E E DZ Random Assignment Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

42. DZ E E c Where do these people “fit” in the 2x2 table? Flow Diagram 2x2 Table 9. (Answer) DZ E E E E Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

43. DZ E E d Flow Diagram 2x2 Table Where do these people “fit” in the 2x2 table? 10. (Answer) E E DZ Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

44. CDC Does this all make sense to you? There are four basic study designs for testing hypotheses. Each design has a different plan for assessing exposure and disease. The plan for each design can be understood by: 1) thinking of a train ride from exposure to disease, and 2) constructing a flow diagram. Whatever the study design, the assessment of exposure and disease “fits” into a 2x2 table so that a sample’s exposure and disease can be classified, risks calculated, risks compared, and inferences made. Making Sense Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables

45. CDC Investigation 2-9 has ended. Designs, Diagrams, and Tables Detectives in the Classroom – Investigation 2-9: Designs, Diagrams, and Tables