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1 The study of biochemistry is necessary to understand Microbiology Habitat Diet.

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Presentation on theme: "1 The study of biochemistry is necessary to understand Microbiology Habitat Diet."— Presentation transcript:

1 1 The study of biochemistry is necessary to understand Microbiology Habitat Diet

2 2 Why Chemistry? Conflict between microbe and host. Vibrio cholera toxin inserting into intestinal cells.

3 3 Terms and Definitions to review and Remember: Atom, protons, neutrons, electrons, isotopes, elements, molecules, ions, anions, cations, compounds, covalent bonds, ionic bonds, hydrogen bonds, pH, acids, and bases. Solution Suspension And colloids

4 4 Chemical Reactions Synthesis or decomposition reactions –More when we cover metabolism. ReactantsProducts (general) Substrate(s)Products(enzymatic) C 12 H 22 O 11 + H 2 O 2 C 6 H 12 O 6 Hydrolysis (left to right) Dehydration (right to left) + H2O http://www.unisanet.unisa.e du.au/08365/timages/sucro se.jpg

5 5 Covalent and Hydrogen bonds Water Covalent Bonds: sharing of electrons between the oxygen and hydrogen atoms. Strong. Hydrogen bonds: electrical attraction between electronegative oxygen atom and nearly naked proton. Weak. mdp2.phys.ucl.ac.uk/ Talks/Ice/Ice.html

6 6 H-bonds hold large molecules together Example: A-T base pair in DNA http://www.mun.ca/biology/scarr/Fg10_16a.gif

7 7 Hydrophilic and hydrophobic Surfaces made of molecules without polar groups (e.g. CH 3 CH 2 CH 2 CH 2.) repel water.

8 8 Functional Groups

9 9 Small molecules (monomers) and macromolecules (polymers) Ethylene and polyethylene

10 10 Carbohydrates: CH 2 O Monosaccharides: glucose, fructose, many others Disaccharides: sucrose, lactose Oligosaccharides: found on glycoproteins, in cytoplasm (oligo- means “few”) Polysaccharides: starch, glycogen, agar, chitin, xanthan gum

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14 14 A nucleotide: a monomer of DNA http://www.emc.maricopa.edu/faculty/farabee/BIOBK/nucleotide.gif

15 15 Nucleic acids are the polymers made from nucleotides. DNAtRNA http://www.biochem.uwo.ca/meds/medna/IMG/tRNA.GIF

16 16 The structure of DNA

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18 18 Phospholipids are essential building blocks for membranes; sterol-type molecules are rarely found in bacteria.

19 19 A lipid polymer: a biodegradable plastic made by bacteria.

20 20 Inclusions of PHB in a bacterial cell

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