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© 2006 McGraw-Hill Higher Education. All rights reserved. Chapter 12 Dietary Supplements and Over the Counter Drugs
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© 2006 McGraw-Hill Higher Education. All rights reserved. Dietary Supplements Looks like a drug but not a drug Food, Drug and Cosmetic Act Dose vs. serving size What they say vs. what you get With dietary supplements, 300mg is the size of the pill not the amount of active ingredient Brand to brand and pill to pill ingredients could be different
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© 2006 McGraw-Hill Higher Education. All rights reserved. Dietary Supplements Do not have to prove effectiveness There are seven claims they can make if the product meets certain requirements. DSHEA (1994) Redefined dietary supplement Redefined safety “Well being”
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© 2006 McGraw-Hill Higher Education. All rights reserved. Remember… “This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.”
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© 2006 McGraw-Hill Higher Education. All rights reserved. Saint-John’s-Wort Hypericum perforatum Was used to prevent possession of demons now anxiety and depression Can have negative interactions with prescription drugs
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© 2006 McGraw-Hill Higher Education. All rights reserved. S-adenosyl-L-methionine (SAMe) Active form of amino acid methionine Researched as an antidepressant Ginkgo Biloba Long term use in China for medical use Reduces blood clotting Might improve memory
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© 2006 McGraw-Hill Higher Education. All rights reserved. Over the Counter (OTC) drugs OTC drugs are self-prescribed and self-administered for self-diagnosed illnesses
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© 2006 McGraw-Hill Higher Education. All rights reserved. OTC Label Required label information includes: Approved uses of the product Detailed instructions on safe and effective use Cautions or warnings to those at greatest risk when taking the medication
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© 2006 McGraw-Hill Higher Education. All rights reserved. Psychoactive OTC Stimulants Help restore mental alertness or wakefulness NoDoz – 100 mg of caffeine Weight-Control Products Phenylpropanolamine (PPA) PPA and caffeine together were approved but then ruled unsafe. In 2000 PPA was pulled Ephedra, Benzocaine, starch blockers, Cholecystokinin, as well as others banned. Sedatives and Sleep Aids Scopolamine combined with antihistamine methapyrilene Few still available today
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© 2006 McGraw-Hill Higher Education. All rights reserved. Psychoactive OTC Analgesics Opioids or OTC Scteylastes Acetylsalicylic acid (Aspirin) Analgesics – pain relief Antipyretic – fever reducer Anti-inflammatory – reduces swelling, inflammation and soreness Increases bleeding – inhibits blood platelet aggregation Reye’s syndrome
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© 2006 McGraw-Hill Higher Education. All rights reserved. Psychoactive OTC Acetaminophen Phenacetin and acetaminophen Tylenol COX enzymes NSAIDs Cold, Allergy and Cough Remedies How to control the cold Treatments for the symptoms not the cold Chlorphenramine maleate Dextromethorphan
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