1. Catabolic Pathways 2 nd Year Physiotherapy By Eman Mokbel Alissa, Ph.D.

2. Lecture (1) Contents Metabolism Introduction Thermodynamics Catabolism and Anabolism Metabolic Map Examples of metabolic pathways

3. Lecture (2) Contents Bioenergetics Definition Biomedical Importance Central Reactions of Metabolism ATP as energy carrier ATP, ADP, and AMP structures ATP / ADP Cycle Types of Chemical Bonds Mechanism of Energy Collection Energy currency

4. Lecture (3) Contents Electron Transfer Chain (ETC) Chemiosmotic Hypothesis Conservation of ΔG from NADH oxidation in a pH gradient Respiratory Control

5. Lecture (4) Contents Some Points About Glucose Glucose Oxidation Fate of Glucose Glycolysis ATP and NADH production Alternative Pathways of Pyruvate TCA Cycle Summary of ATP Produced

6. Lecture (5) Contents Fat and Fatty Acids Fatty Acid Oxidation β oxidation ATP Generation from  -Oxidation β-oxidation in peroxisome Unsaturated FA oxidation FA oxidation with odd Carbon No. α-oxidation

7. Lecture (6) Contents Amino acids introduction N2 Metabolism Overall flow of nitrogen in amino acid catabolism Removal of Nitrogen Combined actions of amintoransferase and glutamate dehydrogenase reactions Ammonia transport to liver Urea Cycle Link between urea cycle and TCA cycle