1. Variation Workshop University of Washington March 20-21, 2006 Sponsored by the NHLBI

2. Overview of Workshop Overview of PGAs PGA Education Programs New Opportunities

3. Workshop Overview: Mark Rieder - Finding SNPs Dana Crawford - SNP Selection Debbie Nickerson - SNP Genotyping Chris Carlson - Association Analysis - Tutorials: SNP Resources and Selection - Case Studies - VKORC1 and CRP

4. P ROGRAMS FOR G ENOMIC A PPLICATIONS National Heart, Lung, and Blood Institutes National Institute of Health

5. PGA Mission Provide new resources and reagents to link genes to biological function and make these readily available to the NHLBI community. Facilitate workshops, courses, and visiting scientist programs to train investigators in the technologies being applied in the PGAs. Rapidly disseminate data through the world wide web and public databases.

6. PGA Programs

7. PGA Resources/Tools Mouse Models of HLBS Disorders Rat Models of HLBS Disorders DNA Variations (SNPs - locations, allele frequencies, genotypes and haplotypes) Functionally Conserved Elements (enhancer database) Reagents (clones, ES cells, mice, and rats) Protocols Bioinformatic Resources (software tools and databases) Archives for Microarray and Antibodies

8. http://www.nhlbi.nih.gov/resources/pga/index.htm

9. http://www.nhlbi.nih.gov/resources/pga/resource.htm

10. http://pga.lbl.gov/PGA/PGA_inventory.html

11. PGA Education Programs - http://www.nhlbi.nih.gov/resources/pga/workshop.htm Short Courses On-line Tutorials Visiting Scientist Programs

12. PGA Symposium see http://www.pgasymposium.org

13. New Opportunities from SeattleSNPs