1. Pharmacy Information Resources TTUHSC Preston Smith Library presents Rev. 08/2014

2. EBP Literature from PubMed’s Clinical Queries EBP Literature from PubMed’s Clinical Queries

3. Biomedical and life sciences journal literature PubMed Database International scope Developed and maintained by the: National Center for Biotechnology Information at the U.S. National Library of Medicine at the National Institutes of Health Developed and maintained by the: National Center for Biotechnology Information at the U.S. National Library of Medicine at the National Institutes of Health

4. Accessing PubMed Freely available over the Internet @ www.pubmed.gov Also through library’s home page

5. Evidence-Based Practice is guided by thoughtful integration of the best available scientific knowledge with clinical expertise.

6. tool that searches for evidence-based literature PubMed’s Clinical Queries

7. Diagnosis Therapy Etiology (cause) Prognosis (prediction of probable outcome) Clinical Queries Searchable by:

8. Diagnosis Therapy Etiology (cause) Prognosis (prediction of probable outcome) Clinical Queries Searchable by:

9. uses pre-formulated search strategies with a keyword search PubMed’s Clinical Queries

10. www.ttuhsc.edu/libraries Mouse over Databases Click PubMed

11. Click Clinical Queries

12. Enter asthma Search Click

13. Results for Therapy and Broad Scope Results for Therapy and Broad Scope Change to Narrow Scope

14. Results for Therapy and Narrow Scope Results for Therapy and Narrow Scope Click See all (8382)

15. Click Limits

16. Click Show additional filters

17. Select Languages Select Languages Click Show ✔

18. Click More…

19. Select Meta-Analysis Select Meta-Analysis ✔

20. Click Meta-Analysis to activate filter Click Meta-Analysis to activate filter

21. Results have narrowed to 7 articles

22. Click on the article title you wish to read

23. Click for Free Full Text TTUHSC ONLINE

24. TTUHSC Libraries - Proxy Server A Problems with eRaider call: 806-743-1234 a When Searching from Off Campus: Enter the Eraider username and password assigned to you by Information Services.

25. Click

26. Full Text

27. PubChem

29. Other NLM Databases

30. www.ttuhsc.edu/libraries Click Databases

31. Scroll and click National Library of Medicine Click “N”

32. Click All NLM Databases & API’s

33. Locate and Click Database Name

35. NCBI

36. National Center for Biotechnology Information Mission: create automated systems store and analyze information molecular biology biochemistry genetics facilitate use of databases by the research and medical community

37. Click DNA Helix to go to the NCBI databases Click DNA Helix to go to the NCBI databases

39. National Center for Biotechnology Information Databases AssemblyAssembly GSS (short single-read transcript sequences) BioProjectBioProject HomoloGeneHomoloGene BioSampleNucleotide Database BioSystemsOnline Mendelian Inheritance in Man ClinVarPopSet CloneDBCloneDB ProbeProbe Conserved Domain DatabaseConserved Domain Database Protein DatabaseProtein Database Database of Genomic Structural VariationDatabase of Genomic Structural Variation RefSeqGeneRefSeqGene Database of Genotypes and PhenotypesReference Sequence (RefSeq) EpigenomicsSequence Read Archive EST (short single-read transcript sequences) SNP GeneStructure (Molecular Modeling Database) GenomeGenome TaxonomyTaxonomy GEO Datasets UniGeneUniGene GEO Profiles

40. Search CFTR

41. Click

45. Click Advanced

46. Search

47. 5 variants with sensitivity to Warfarin

48. Have Questions?

49. www.ttuhsc.edu/libraries email us

50. Thank You!