1. Name of Presentation Added in Header Box
Digital Pathology:
The Role of APLIS Integration in
Supporting the Pathologists’ Workflow
Curtis Stratman
Partha Boocha
Andrew Kotov
Vanja Kvarnstrom
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Omnyx, LLC, Pittsburgh, PA

2. Name of Presentation Added in Header Box
DISCLOSURES
Employee of Omnyx, LLC

3. BACKGROUND: This Question is Often Asked
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BACKGROUND: This Question is Often Asked
How do APLIS and digital pathology systems work together to enable an efficient all digital workflow for high-volume routine use?
Interfaces exist today, but one has yet achieved this goal.

4. BACKGROUND: Values Cannot Be Achieved Without Solution
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BACKGROUND: Values Cannot Be Achieved Without Solution
Save pathologist time:
eliminate sorting of and searching for slides
immediate access to prior cases
Optimize utilization of pathologists:
distribute workload across locations
route cases to knowledge experts
Provide additional tools:
precision measurement
document interpretation with tissue region
And more…

5. DESIGN: Workflow Informs Interface Requirements
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DESIGN: Workflow Informs Interface Requirements
Methodology to define integration needs:
Model the current state workflow
Identify when data is created
2. Design the future state workflow
- Identify when data is used
Define the data interface specification
- Provide the right information at the right time for the user
- Balance technical trade-offs

6. RESULT: Leverage Tools from Service Modeling
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RESULT: Leverage Tools from Service Modeling

7. RESULT: Triggers Drive Workflow Actions
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RESULT: Triggers Drive Workflow Actions

8. RESULT: Pathologists’ Workflow is Slide-driven
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RESULT: Pathologists’ Workflow is Slide-driven

9. RESULT: Pathologists’ Workflow is Slide-driven
United States
United Kingdom
France

10. RESULT: Images Alone Do Not Fill the Hole
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RESULT: Images Alone Do Not Fill the Hole
PathologistWorkflow
Slides
Images
What tells pathologists a case is ready for review?
How do pathologists manage their workload?

11. RESULT: Digital Workflow Requires Tight Integration
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RESULT: Digital Workflow Requires Tight Integration
Key Insights:
Imaging workflow inserts activity of Scanning between Histology and Case Review
Case review is triggered by imaging activity of scanning
Case Review is where data from APLIS and imaging system come together for use
Data from many points in workflow is leveraged by pathologist at time of Case Review

12. CONCLUSION: Neither System Can Deliver Alone
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CONCLUSION: Neither System Can Deliver Alone
APLIS has data:
Patient and case records
Case details and documentation
Tissue and processing details
Slide identification and tracking
Digital imaging system has data:
Slides images
Additional slide tracking details
Image archival management
Documentation of image analysis
Workflow needs data from both to do:
Assemble and present digital cases
Alert to pathologist of ready work
Organize and manage workload

13. CONCLUSION: Summary and Next Steps
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CONCLUSION: Summary and Next Steps
Existing APLIS digital pathology interfaces focus on minimizing data transfer to:
Attach images into the current slide-driven APLIS workflow
Provide metadata to display around an image viewer
However, a slide-driven workflow will not function when images replace slides and images alone do not provide a workflow
Therefore, a new image-driven workflow module is needed to deliver an efficient value-add all digital workflow
And as neither an APLIS nor a digital pathology system can deliver this module without the supporting data from the other
We conclude that even though the interface specification to provide workflow integration across systems is more technical effort, doing so is necessary to enable the adoption of digital pathology for routine use.