1. Systematic Review Data Repository (SRDR™) The Systematic Review Data Repository (SRDR™) was developed by the Tufts Evidence-based Practice Center (EPC), Boston, Massachusetts, under contract with the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD (Contract No. HHSA 290-2007-10055-I).

2. What Is the Systematic Review Data Repository (SRDR)? SRDR is a powerful and easy-to-use, Web- based tool for conducting systematic reviews. Searchable archive of key questions from included systematic reviews, and of data from their associated studies. 2 http://srdr.ahrq.gov

3. 3 A repository for SR data will improve efficiency, data quality, transparency, and usability. Why SRDR?

4. Potential SRDR User 4 http://srdr.ahrq.gov Funders of Research Patients Policy Makers, Stakeholders Independent Researchers Research Centers

5. System Status System has been in development for 2 years Launched in June 20 th 2012 Hosted on the AHRQ server Trademarked as Systematic Review Data Repository (SRDR) SRDR is committed to a policy of Open Access. All completed systematic review projects deposited in the SRDR archive are publically available under the terms of a Creative Commons license. Initial data contributors will be members of the EPC and other participating organizations 5http://srdr.ahrq.gov

6. Privileges of SRDR Users Public Can view any study within the database, but cannot post comments. Commentator Privileges of public viewer Can post comments on studies Contributors Privileges of commentator Can modify any study they create under the project they collaborate on View other studies within their project but cannot edit them See project details but cannot edit them View the extraction form but cannot edit it 6 http://srdr.ahrq.gov

7. Current Features Interfaces for creating extraction forms and extracting study data are in place, with improvements being continually implemented Certified data contributors may create extraction form templates and extract data into the system Upon completion of a systematic review project, users may choose to release their extraction forms and corresponding data to the public Tools for data retrieval/summarization and sharing have been developed, with new features in the pipeline Training materials including user manual, instructional videos, and an FAQ are available in the Help section linked to the SRDR homepage Certification procedures and training for data contributors are in place Plans for user support and data backups have been put into practice 7http://srdr.ahrq.gov

8. 8 SRDR Home Page AHRQ banner Latest published projects Data Commentator and Contributors login Link to ‘Testing Site’

9. Public View 9http://srdr.ahrq.gov

10. Commentator Access 10 http://srdr.ahrq.gov

11. Contributor Access 11http://srdr.ahrq.gov

12. Steps for Data Contributor Create ProjectEnter Key Question(s) Create Extraction Form(s) Extract Study Data Review and Publish Report Data 12 http://srdr.ahrq.gov

13. System Structure Project: All data deposited within the SRDR are organized as individual projects. A project contains all information related to one systematic review (e.g., extraction forms, key questions, extracted studies, etc.) Key Question(s): The specific scientific queries an SRDR project is intended to address. All projects must include at least one key question Extraction Form: The user-defined dialogue by which collaborators extract data from relevant publications into an SRDR project Study: An individual publication extraction, consisting of one instance of a filled out extraction form 13http://srdr.ahrq.gov

14. Data Contributor Certification Process 14 Step 1 Attend training session conducted by the SRDR team Step 2 Enter 2 training cases into SRDR training site Step 3 Have the first few records entered to the production site reviewed by SRDR team prior to ‘publication’ in the system. Step 4 Change the status from ‘New user’ to ‘Certified user’ http://srdr.ahrq.gov

15. Support Plan Online support The SRDR system will offer free online support to all user types along with a user manual and instructional videos. Another support platform is the user-supported forum where reviewers are encouraged to post, as well as answer questions. The SRDR Support Team will also monitor the forums and answer questions. Direct Support Direct support is also available at no cost to the user. Direct support would provide guidance for activities such as setting up the review, importing of search results, and reviewing specific help/suggestions about optimal use of the software. Technical and content questions/issues will be referred to the Technical Team via the following methods: Automatically – user will use the FEEDBACK feature in the system Phone/email – individual user and/or ‘SRDR Administrator’ will refer the question/issue to the SRDR Support Team 15 http://srdr.ahrq.gov

16. What Are the Benefits of SRDR? SRDR can save valuable time by: Downloading study information from PubMed® (and from other databases in the near future) automatically. Quickly creating complex extraction forms, which can accommodate any study design or research question via the form design tool’s powerful and flexible “question builder” capability. Enabling easy comparison and reconciliation of double data extractions. Seamlessly saving all data online. (You can also export your data in a variety of formats for local backup, printing, or analysis using your favorite software package.) 16 http://srdr.ahrq.gov

17. Other Benefits SRDR’s built-in messaging and commenting system makes it easy to coordinate with team members. SRDR can be easily incorporated into workflow. Plan to integrated with other systematic review tools such as Abstracker and OpenMeta. In addition to creating and managing systematic review projects, you can search completed projects that have been submitted to the public archive, and easily update your files, copying previously extracted study data into your own. http://srdr.ahrq.gov 17

18. How Can We Get Started? The SRDR Web site contains a user’s manual as well as instructional videos to help you get the most out of this powerful tool. To get started, or to learn more, just visit www.srdr.ahrq.gov www.srdr.ahrq.gov 18 http://srdr.ahrq.gov

19. SRDR Demonstration http://srdr.ahrq.gov Create a project Extraction form Extracted study data Special features Search Commenting Exporting Table creator Double extraction 19