1. 1 Opportunity #4: Encouraging a greater focus on global health

2. 2 Emphasis on global health fits with U.S. emphasis on “soft power” Scientific advances make an attack on infectious diseases more feasible than ever –RNAi –Small molecule screening –Genomics –Vaccine development Push beyond AIDS, malaria, TB to the long list of neglected tropical diseases (NTDs) that affect hundreds of millions of people worldwide Include chronic noncommunicable diseases and injuries, now responsible for more than half of the deaths in the developing world Opportunity #4: Encouraging a greater focus on global health

3. 3 Opportunity #5: Reinvigorating and empowering the biomedical research community Great projects outside the box

4. 4 Emphasis on innovation –Pioneer awards –New Innovator awards –Transformative RO1s Continuing to innovate in peer review Reinvigorating the Common Fund –Seven new programs in 2010 Training and career development programs –Seek to reduce age at first grant award –Encouraging underrepresented groups – Pathfinder Award –Women in science Opportunity #5: Reinvigorating and empowering the biomedical research community

5. 5 NIH BUDGET & RESEARCH INITIATIVES: STIMULATED BY ARRA

6. 6 NIH Congressional Appropriations FY1997- FY2009 (dollars in billions)

7. 7 NIH is grateful to President Obama, Congress, and the American people for the opportunity for NIH to play its part in improving the Nation’s health and economy. American Recovery and Reinvestment Act of 2009 ARRA

8. NIH ARRALANCHE!!!

9. 9 NIH ARRA by the Numbers Of the $10 Billion appropriated directly to NIH* Approximately $6.3B has been awarded as of April 2010 –$5.7B in grants to over 15,000 projects –$565M in contracts to over 683 projects 2,346 new investigators 32 institutions are first-time NIH awardees, 18 of which are small businesses Estimated job creation/retention: 50,000 over 2 years *Recovery Act also appropriated $0.4 Billion for Comparative Effectiveness Research through AHRQ

10. 10 NIH FY 2011 President’s Budget Request $32.2 Billion Increase of $1B or 3.2% over FY 2010 non-ARRA dollars *ARRA Funding: $5B for FY 2009, $5B for FY 2010 Annual levels represent total budget authority, including special type 1 diabetes appropriation * * The cliff

11. 11 Health Care Reform