1. GI Sequence - Histology Small and Large Intestines Recto-anal junction January 14, 2009 Sun-Kee Kim / Andy Chervenak

2. #29 Small Intestine Mesentery (ct + epithelium) Submucosa (connective tissue) Mucosa (epithelium + lamina propria) Muscularis Externa (smooth muscle) Lumen Muscularis mucosae

3. #29 – Intestinal Villi Intestinal villi

4. #29-Simple columnar epithelium with striated border (microvilli) and goblet cells Microvilli (striated border) Goblet cells Enterocytes ?

5. #165 (PAS)-Goblet cells distributed throughout villi and crypts

6. Pyloric Stomach Pylo-duodenal junction (arrow) Pyloric sphincter muscle

7. #161 Pylo-duodenal J. with Pancreas Pyloric stomach Duodenum Pancreas

8. #161 Muscularis mucosae Lymphatic nodules Brunner’s gland

9. #161, 162 Duodenum Lumen Intestinal villus Muscularis mucosae ? ? crypts or i. glands Brunner’s glands pancreas

10. #29, 168, 169, 170 Jejunum or Ileum lumen submucosa Muscularis mucosae Crypts of Lieberkuhn

11. #29, Intestinal glands (crypts) Paneth cells Enteroendocrine cells Mitotic cell ? ? ?

12. #246 Enteroendocrine cell Paneth cell

13. #29, Myenteric (Auerbach’s) plexus Ganglion cells

14. #176, 177: Colon (Mucosa of the colon) m.m No villi, Straight glands, lots of goblet cells

15. #176 – colon mucosa

16. #175: Appendix Mucosa is like colon: no villi, straight glands Muscularis externa is like small intestine: Two layers of s. muscle Heavy infiltration of lymphatic tissues forming nodules.

17. #177-1, 177-3, 177-2 Recto-anal junction Hemorrhoidal veins Muscularis mucosae Type of epithelium changes Muscularis mucosae frays Dilated veins

18. #177-1, 177-2, 177-3 Recto-anal junction Internal anal sphincter (sm. muscle) External anal sphincter (skel. muscle) Hair follicle w/ sebaceous and sweat glands

19. Cardio-esophageal junction (arrow)

20. Chief cells Paneth cellsParotid gland acinar cells von Ebner’s gland Mixed salivary glands Serous acinar cells Serous demilune cells

21. #170 Small Intestine

22. #194 Gallbladder Mucosa epithelium lamina propria Smooth muscle Adventitial c.t. Liver Simple columnar ep.