1. Undifferenciated sarcoma 2012-05983 MH

2. Female 67 years old Weight loss 15 kg Self palpation a mass of proximal thight 2012-05983 MH

3. MRI April 2012

4. Per cutaneous biopsy Undifferenciated sarcoma Grade 3 Chest CT: Normal 2012-05983 MH Ki-67

5. 2012-05983 MH 67 years old MRI April 2012 What do you propose? Front line surgery? Radiotherapy? Chemotherapy?

6. 2012-05983 MH What do you propose? Front line surgery? Radiotherapy? Chemotherapy? A 60 mg/m2 J1 I: 3g/m2 J1 J2 67 years old MRI April 2012

7. June 2012: post 2 cycles CT: + 3 cm 2012-05983 MH

8. What do you propose? Surgery? Radiotherapy? 2 nd line chemotherapy?

9. October 2012: Post RT 50 Gy: - 2 cm 2012-05983 MH

10. Surgery oct 2012

12. 15 X 7 cm Femoral nerve is included Vessels partially included 8% residual tumour cells R0 1 mm Pathology 2012-05983 MH

13. June 2014: MRI Chest CT: normal + 2 years 2012-05983 MH