2. BY: ELENA SEIFERT & KRISTEN THORNE PERIOD 8 1/8/14 Pituitary Gland Posterior Lobe

3. Location Part of the brain

4. What type of hormones are produced? ADH (antidiuretic hormone) Oxytocin

5. How do these hormones affect the body? ADH- Promotes reabsorption of water by the kidneys Oxytocin- strongly affects human social interactions, stimulates uterine contractions during childbirth and facilitates breast feeding  AKA the “love hormone”

6. Maintenance of homeostasis ADH- helps maintain water and electrolyte balance The pituitary and the hypothalamus glands work together to regulate the release of other hormones in the body.

7. Feedback Mechanisms ADH- when there is not enough water in the blood ADH is secreted so the kidneys reabsorb water (negative feedback) Oxytocin- during childbirth, oxytocin is released to stimulate uterine contraction and lactation from the mammary glands (positive feedback)

8. Antagonistic Hormones Vasopressin Receptor Antagonist (VRA)- blocks ADH for those with congestive heart failure Atosiban (oxytocin receptor antagonist)- blocks Oxytocin to control emotions and hormones

9. Disorders With a damaged or malfunctioning pituitary gland, your body would lose the normal ability to regulate the hormones released by most endocrine glands. Disorders of the posterior pituitary gland are:  diabetes insipidus  Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

10. Diabetes insipidus Condition where the kidneys are unable to conserve water due to lack of ADH Symptoms-  Extreme thirst  Excessive urine volume Treatment-  Medication (vasopressin)

11. SIADH Condition where high levels of ADH cause the kidneys to absorb excessive amounts of water. Symptoms-  Nausea/vomiting  Cramping  Seizures  Coma Treatment-  Surgery to remove the gland releasing ADH  Medication to block ADH

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