1. Proposed Synthesis of Haliclonin A Stefan Breitenlechner, Angélique Fortier, James Mousseau, Marie-Noelle Roy, Frédéric Vallée aka: 7 th Heaven

2. 2 Retrosynthetic Analysis

3. 3 Diels-Alder Precursors

4. 4 D-A Cascade

5. 5 Yamamoto, Y., et al. Chem. Rev. 1993, 93, 2207

6. 6 Onward and Upward

7. 7 More Cascades

8. 8 Aziridination

9. 9 Towards the End

10. 10 Cyclization/Endgame Farina, V. et al. Org. Proc. Res. Dev. 2009, 13, 250 (15)

11. 11 Summary 25 linear steps 2 ‘Cascade’ reactions Projected overall yield: 98.2% Actual overall yield: 85.4% Manuscript in preparation

12. 12 Proof