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The members of the IsdG family of heme oxygenases are widely distributed in bacteria and are present in all three domains of life. The members of the IsdG family of heme oxygenases are widely distributed in bacteria and are present in all three domains of life. Data represent a maximum likelihood phylogeny of the IsdG heme oxygenase protein family. The tree was rooted at the midpoint and visualized using iTOL version 3.0. Color strips along the tree perimeter correspond to the taxonomy (inner strip) and the number of conserved IsdG family catalytic residues contained within each protein sequence (outer strip). Red tick marks indicate the IsdG family enzymes that were previously functionally characterized. Lisa J. Lojek et al. mSphere 2017; doi: /mSphere
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