1. Isolation and phylogenetic characterization of ISS strains.
Isolation and phylogenetic characterization of ISS strains. (A) IF1SW-F4 was isolated from the wall area outlined in blue adjacent to the cupola window aboard the ISS. ISSFT-021 was independently isolated from a HEPA filter (not shown). (B) Frequency distribution of total SNPs found in 94 sequenced clinical and environmental isolates of A. fumigatus in comparison to a reference genome (Af293). Colored arrows designate the bin groups to which each strain included in this study belongs. (C) Phylogenetic tree of 95 sequenced isolates of A. fumigatus, showing mating type (MAT1-1 or MAT1-2), clinical or environmental origin, and geographical sampling location. Strains of interest used in this study are highlighted in yellow.
Benjamin P. Knox et al. mSphere 2016; doi: /mSphere