Presentation is loading. Please wait.

Presentation is loading. Please wait.

Enrichment of two rare SNPs among ABC DLBCL tumors.

Published bySüleyman Atalay Modified over 4 years ago

Similar presentations

Presentation on theme: "Enrichment of two rare SNPs among ABC DLBCL tumors."— Presentation transcript:

1 Enrichment of two rare SNPs among ABC DLBCL tumors.
Enrichment of two rare SNPs among ABC DLBCL tumors. A, amino acid sequence (based on accession NP_060469) of a region of the UBA domain of RNF31 showing the residues altered by two SNPs, Q584H and Q622L, and the number and type of lymphoma biopsies in which they were identified. B, location of the residues altered by the RNF31 SNPs in two views of the three-dimensional structure of the RNF31 UBA domain. C, frequencies of RNF31 SNPs in biopsy samples from different lymphoma subtypes. Yibin Yang et al. Cancer Discovery 2014;4: ©2014 by American Association for Cancer Research

Download ppt "Enrichment of two rare SNPs among ABC DLBCL tumors."

Similar presentations

FINAL EXAM: TAKE-HOME Assessment of Significance in Cancer Gene SNPs.

FINAL EXAM: TAKE-HOME Assessment of Significance in Cancer Gene SNPs.
EBV-positive diffuse large B-cell lymphoma of the elderly by Chi Young Ok, Thomas G. Papathomas, L. Jeffrey Medeiros, and Ken H. Young Blood Volume 122(3):328-340.

EBV-positive diffuse large B-cell lymphoma of the elderly by Chi Young Ok, Thomas G. Papathomas, L. Jeffrey Medeiros, and Ken H. Young Blood Volume 122(3):
Homozygous deletions within chromosome 9q23.

Homozygous deletions within chromosome 9q23.
Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells by Jonathan M. Irish,

Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells by Jonathan M. Irish,
The cBio Cancer Genomics Portal.

The cBio Cancer Genomics Portal.
Minimal Residual Disease Measurement By Deep Sequencing Reflects Changes In Disease Load During Therapy In Diffuse Large B Cell Lymphoma Patients by Nina.

Minimal Residual Disease Measurement By Deep Sequencing Reflects Changes In Disease Load During Therapy In Diffuse Large B Cell Lymphoma Patients by Nina.
Regional lymph nodes and distal extracranial metastases are not a reliable surrogate for actionable mutation in brain metastases. Regional lymph nodes.

Regional lymph nodes and distal extracranial metastases are not a reliable surrogate for actionable mutation in brain metastases. Regional lymph nodes.
Enrichment of sequence disorder in the cytosolic phosphoproteome.

Enrichment of sequence disorder in the cytosolic phosphoproteome.
AZD9291 binding mode and structure.

AZD9291 binding mode and structure.
Key amino acid positions identified by association analysis are highlighted in three-dimensional ribbon models for the HLA-DR, HLA-DQ, HLA-A and HLA-DP.

Key amino acid positions identified by association analysis are highlighted in three-dimensional ribbon models for the HLA-DR, HLA-DQ, HLA-A and HLA-DP.
Five independent associations were identified after stepwise association analysis within the MHC region at the discovery stage. Five independent associations.

Five independent associations were identified after stepwise association analysis within the MHC region at the discovery stage. Five independent associations.
Identification of Somatic Mutations in Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type by Massive Parallel Sequencing  Sylvain Mareschal, Anne.

Identification of Somatic Mutations in Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type by Massive Parallel Sequencing  Sylvain Mareschal, Anne.
Multiple sequence alignment and analysis of SOFL proteins.

Multiple sequence alignment and analysis of SOFL proteins.
Genomic alterations in breast cancer cell line MDA-MB-231.

Genomic alterations in breast cancer cell line MDA-MB-231.
Diagnostic approaches to measure the impact of cancer therapies on clonal evolution. Diagnostic approaches to measure the impact of cancer therapies on.

Diagnostic approaches to measure the impact of cancer therapies on clonal evolution. Diagnostic approaches to measure the impact of cancer therapies on.
Copy-number alterations in an archival breast cancer sample.

Copy-number alterations in an archival breast cancer sample.
Potential clinical actionability.

Potential clinical actionability.
Antigen-specific TCRβ clonotypes map to the TCRβ repertoire at markedly different frequencies. Antigen-specific TCRβ clonotypes map to the TCRβ repertoire.

Antigen-specific TCRβ clonotypes map to the TCRβ repertoire at markedly different frequencies. Antigen-specific TCRβ clonotypes map to the TCRβ repertoire.
Identification of a MEK2 mutation in a melanoma sample resistant to dabrafenib/trametinib. Identification of a MEK2 mutation in a melanoma sample resistant.

Identification of a MEK2 mutation in a melanoma sample resistant to dabrafenib/trametinib. Identification of a MEK2 mutation in a melanoma sample resistant.
Distribution of intrinsic subtypes among TNBC and distribution of TNBC among basal-like breast cancer. Distribution of intrinsic subtypes among TNBC and.

Distribution of intrinsic subtypes among TNBC and distribution of TNBC among basal-like breast cancer. Distribution of intrinsic subtypes among TNBC and.

Similar presentations

Ads by Google