2. © 2008 OSIsoft, Inc. | Company Confidential Enterprise Agreement Services & Bristol-Myers Squibb: Devens Case Study Don Smith (OSIsoft) Todd Brown (OSIsoft) Ashley Howard (Bristol-Myers Squibb) Don Smith (OSIsoft) Todd Brown (OSIsoft) Ashley Howard (Bristol-Myers Squibb)

3. 3 © 2008 OSIsoft, Inc. | Company Confidential Enterprise Agreement Experiences Customers recognize the value of OSIsoft products in generating or supporting the generation of ROI for the enterprise Achieve a step change in adoption and value –Rock Tenn – 12 mills Create real-time infrastructure Asset model view + Energy, Production and KPIs System Integrator project services –Cemex – 77 plants Rollout to 77 sites, 4 continents Consistent site reporting, enterprise visibility Enterprise application deployment

4. 4 © 2008 OSIsoft, Inc. | Company Confidential What Is Included 1.Standard OSIsoft PI Infrastructure Software –The scope of provides unlimited quantities of the Eligible Products 2.Managed PI (mPI) Software –mPI software includes software to help install, manage and update the Standard OSIsoft PI Infrastructure 3.Managed Services –These include bundled services from OSIsoft to help the customer gain business value from the PI Infrastructure Software.

5. 5 © 2008 OSIsoft, Inc. | Company Confidential Managed Services Enterprise Program Management (EPM) – customer advocate –Dedicated contact - focal point from OSIsoft –Customer advocate to drive the installation and adoption of the infrastructure Installation Services – PI installed and current –Install and upgrade the software provided –Remote & automated manner by default (mPI) Technical Support Services – keep PI tuned up –Standard 7x24 support access via phone, email, etc. –NOC keep the PI Infrastructure operating at a high level of availability and performance. Education Services –Onsite, Offsite, Webinar, CBT (Saleable) Value Engineering Advisory Services (CoE) – more business value –CoE provides Value Engineering Advisory Services –Helping customers to gain high value and minimal risk

6. 6 © 2008 OSIsoft, Inc. | Company Confidential Links Managed Services & PI Infrastructure Manage situations with data - updates Allows Scale of Managed Services –Today: NOC – detect problems at OSIsoft Updates/Status – inventory managed Extranet – visibility of status, reports –Future: Installs – modern update management Delivery Collaboration –EPM, CoE, Tech Support –Education – Webinar Repository –CoE: Virtual Campus Private Areas The Role of mPI

7. 7 © 2008 OSIsoft, Inc. | Company Confidential Project Overview – Facility Scope BMS is investing $750 million in the construction of a Large-Scale Cell Culture (LSCC) manufacturing facility for the commercial production of biopharmaceuticals in Devens, MA. This facility will have 120,000 liters of bioreactor capacity. Designed for concurrent multi-product production.

8. 8 © 2008 OSIsoft, Inc. | Company Confidential 20102009 Ground Breaking Operationally Complete FDA Submission Project Overview – Facility Timeline Implement a fully automated, paperless solution that supports release by exception utilizing S95/S88 integrated recipe Mar 2007

9. 9 © 2008 OSIsoft, Inc. | Company Confidential MFG Building Lab Offices WH/Chem Storage Trailers CUB Project Overview – Site Progress

10. 10 © 2008 OSIsoft, Inc. | Company Confidential The Need for Innovation through Automation Inconsistent execution, lack of automation => lost batches, quality & GMP issues Paper-based =>long cycle times, increased WIP Lack of standards => inefficient tech development and transfer Limited data capture, no enterprise intelligence framework => impacts operations support, optimization Manuf. and lab systems not integrated => scheduling inefficiencies

11. 11 © 2008 OSIsoft, Inc. | Company Confidential LSCC Business Requirements Reduce Process Deviations Automated Equipment Electronic Work Instructions Equipment Tracking Recipe Driven Operations Expedite Batch Review & Release Electronic Data Capture Exception Reporting Recipe Driven Operations Improve Inventory Management Material Tracking Weigh and Dispense Recipe Driven Operations Drive Standardization Utilize Industry and Corporate Standards Recipe Driven Operations

12. 12 © 2008 OSIsoft, Inc. | Company Confidential LSCC Systems Overview

13. 13 © 2008 OSIsoft, Inc. | Company Confidential CoE: The Center of Excellence Services Evangelism Support Evangelism Support Proof of Technology Proof of Technology General Systems Support General Systems Support Core ServicesSupport Services Tactical Strategic

14. 14 © 2008 OSIsoft, Inc. | Company Confidential Bristol-Myers Squibb & OSIsoft EA Value: Center of Excellence Services (by the Numbers) Total # BMS CoE Engagements (Jan08 – Oct08): 26

15. 15 © 2008 OSIsoft, Inc. | Company Confidential EA: Driving New Interface Development PI Enterprise Option with DeltaV Smart Connector –New historian option in DeltaV 10.3 DeltaV Batch Smart Connector –Joint architecture approved by OSIsoft & Emerson –Dual sourced data from OPC A&E Server & Batch Historian Emerson Compliance Suite Smart Connector –Extends the context of the Batch from the S88 level to include the S95 level –Captures the integrated Recipe: both automated recipe steps and electronic work instructions into PI Batch Database Start Batch Prepare (W&D, Room/Personnel Status) Pressure Test & CIP Reactor Finish Batch Collect Sample & Analyze React Separate CIP Dryer Drying Verify Bag Filler Status Operate Bag Filler Manual Activities in Manufacturing Engine MES Automated Activities in Batch Execution Engine DCS

16. 16 © 2008 OSIsoft, Inc. | Company Confidential EA: Enabling Enterprise Architecture Standards Option 1 Option 2 Option 3Option 4

17. 17 © 2008 OSIsoft, Inc. | Company Confidential EA: Developing Solutions Architectures Biz Goals Tech Goals GAP Analysis Future State Current State Project Advisory

18. 18 © 2008 OSIsoft, Inc. | Company Confidential EA: Driving Industry Best Practices: Best Practice for Validating the PI Infrastructure Benchmark the industry Develop Validation Principles Define Streamlined Requirements Develop Validation Templates Test Drive in Actual Project & Adjust Course Rollout to our EAs in the Industry Foster Continuous Improvement

19. 19 © 2008 OSIsoft, Inc. | Company Confidential Happy EA Customer Common Traits Purchase to support a step change in use of PI software. More information –18:30 Theater 3 - mPI/NOC –Wednesday 14:20 – Details of the EA Program –Wednesday 16:30 – Process Data an Enterprise Asset at Bayer MaterialScience

20. 20 © 2008 OSIsoft, Inc. | Company Confidential Managed Services Kudos I wanted to thank you …. they DID help me a lot in my steering committee presentation on Friday. It allowed me to demonstrate that we get good value indeed out of our CoE partnership with OSIsoft! Your staff were knowledgeable, cooperative and reliable in their statements and commitments. In short, the team are very pleased with the conduct and result of the exercise. Let me add that your responsiveness in terms of the timing of making staff available was very much appreciated. The final document was well written with good recommendat ions that had captured the overall HA requirements/design. All are well in scope. Thanks again for the effort and the professional services rendered. The services provided with this enterprise agreement went well beyond what we are used to from traditional software vendors. This is a true partnership Very much Appreciated!!! You are going above and beyond the call of duty and I for one very much appreciate the effort this takes. I am confident we will come out with a landmark set of documents that will not only avail themselves to faster, leaner testing but also be carried forward for all future sites. And many more…

21. 21 © 2008 OSIsoft, Inc. | Company Confidential Questions?

22. 22 © 2008 OSIsoft, Inc. | Company Confidential