Presentation is loading. Please wait.

Presentation is loading. Please wait.

Jorge D. Salazar, MD, Ryan D

Published byΝικομήδης Αβραμίδης Modified over 5 years ago

Similar presentations

Presentation on theme: "Jorge D. Salazar, MD, Ryan D"— Presentation transcript:

1 Selective Cerebral Perfusion: Real-Time Evidence of Brain Oxygen and Energy Metabolism Preservation 
Jorge D. Salazar, MD, Ryan D. Coleman, BA, Stephen Griffith, MD, Jeffrey D. McNeil, MD, Megan Steigelman, MD, Haven Young, CCP, Bart Hensler, CCP, Patricia Dixon, MS, John Calhoon, MD, Faridis Serrano, PhD, Robert DiGeronimo, MD  The Annals of Thoracic Surgery  Volume 88, Issue 1, Pages (July 2009) DOI: /j.athoracsur Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Example of operative technique used for selective cerebral perfusion. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Cerebral tissue oxygenation is shown in piglets undergoing deep hypothermic circulatory arrest (DHCA) with or without selective cerebral perfusion (SCP). Cerebral tissue oxygenation (Pbto2) is shown as relative units (RU), normalized to before cardiopulmonary bypass baseline (BL; mm Hg). Measurements are shown at the following times: BL, before cardiopulmonary bypass baseline; Cool, cooling; CA30, 30 minutes of DHCA; eCA, end DHCA; RW, rewarming; eCB, end CPB. dp < 0.001, cp < 0.01. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Cerebral microdialysis glycerol is shown in piglets undergoing deep hypothermic circulatory arrest (DHCA) with or without selective cerebral perfusion (SCP). Measurements are shown at the following times: BL, before cardiopulmonary bypass baseline; Cool, cooling; CA30, 30 minutes of DHCA; eCA, end DHCA; RW, rewarming; eCB, end CPB. dp < 0.001; cp < 0.01. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Cerebral microdialysis lactate to pyruvate (L/P) ratio is shown in piglets undergoing deep hypothermic circulatory arrest (DHCA) with or without selective cerebral perfusion (SCP). Measurements are shown at the following times: BL, before cardiopulmonary bypass baseline; Cool, cooling; CA30, 30 minutes of DHCA; eCA, end DHCA; RW, rewarming; eCB, end CPB. dp < 0.001, cp < 0.01, bp < 0.05. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

6 Fig 5 Linear regressions are shown for measurements of glucose (A), pyruvate (B), and lactate to pyruvate (L/P) ratio (C) versus cerebral tissue oxygenation (Pbto2). Regressions are shown with 95% confidence and prediction limits for data points, shown as inner and outer lines, respectively. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Download ppt "Jorge D. Salazar, MD, Ryan D"

Similar presentations

Direct Spinal Cord Perfusion Pressure Monitoring in Extensive Distal Aortic Aneurysm Repair  Christian D. Etz, MD, PhD, Gabriele Di Luozzo, MD, Stefano.

Direct Spinal Cord Perfusion Pressure Monitoring in Extensive Distal Aortic Aneurysm Repair  Christian D. Etz, MD, PhD, Gabriele Di Luozzo, MD, Stefano.
Comparative study of retrograde and selective cerebral perfusion with transcranial Doppler  Yoshihisa Tanoue, MD, Ryuji Tominaga, MD, Yoshie Ochiai, MD,

Comparative study of retrograde and selective cerebral perfusion with transcranial Doppler  Yoshihisa Tanoue, MD, Ryuji Tominaga, MD, Yoshie Ochiai, MD,
Elaine E. Tseng, MD, Malcolm V. Brock, MD, Mary S. Lange, MA, Juan C

Elaine E. Tseng, MD, Malcolm V. Brock, MD, Mary S. Lange, MA, Juan C
Deep Hypothermic circulatory arrest does not impair neurodevelopmental outcome in school-age children after infant cardiac surgery  Stephanie Fuller,

Deep Hypothermic circulatory arrest does not impair neurodevelopmental outcome in school-age children after infant cardiac surgery  Stephanie Fuller,
Cerebral Oxygen Saturation Does Not Normalize Until After Stage 2 Single Ventricle Palliation  Kathleen N. Fenton, MD, Katherine Lessman, BS, Kimberly.

Cerebral Oxygen Saturation Does Not Normalize Until After Stage 2 Single Ventricle Palliation  Kathleen N. Fenton, MD, Katherine Lessman, BS, Kimberly.
Prolonged White Matter Inflammation After Cardiopulmonary Bypass and Circulatory Arrest in a Juvenile Porcine Model  Ludmila Korotcova, MD, Sonali Kumar,

Prolonged White Matter Inflammation After Cardiopulmonary Bypass and Circulatory Arrest in a Juvenile Porcine Model  Ludmila Korotcova, MD, Sonali Kumar,
A Closed Perfusion System With Heparin Coating and Centrifugal Pump Improves Cardiopulmonary Bypass Biocompatibility in Elderly Patients  Lena Lindholm,

A Closed Perfusion System With Heparin Coating and Centrifugal Pump Improves Cardiopulmonary Bypass Biocompatibility in Elderly Patients  Lena Lindholm,
Anaerobic Metabolism During Cardiopulmonary Bypass: Predictive Value of Carbon Dioxide Derived Parameters  Marco Ranucci, MD, Giuseppe Isgrò, MD, Federica.

Anaerobic Metabolism During Cardiopulmonary Bypass: Predictive Value of Carbon Dioxide Derived Parameters  Marco Ranucci, MD, Giuseppe Isgrò, MD, Federica.
Regulation of Brain Cell Death and Survival After Cardiopulmonary Bypass  Tatiana Zaitseva, PhD, Steven Schultz, MD, Gregory Schears, MD, Peter Pastuszko,

Regulation of Brain Cell Death and Survival After Cardiopulmonary Bypass  Tatiana Zaitseva, PhD, Steven Schultz, MD, Gregory Schears, MD, Peter Pastuszko,
Regional low-flow perfusion provides somatic circulatory support during neonatal aortic arch surgery  Frank A Pigula, MD, Sanjiv K Gandhi, MD, Ralph D.

Regional low-flow perfusion provides somatic circulatory support during neonatal aortic arch surgery  Frank A Pigula, MD, Sanjiv K Gandhi, MD, Ralph D.
Harm H. H. Feringa, MD, Leslee J

Harm H. H. Feringa, MD, Leslee J
Effects of pH Management During Selective Antegrade Cerebral Perfusion on Cerebral Microcirculation and Metabolism: Alpha-Stat Versus pH-Stat  Sebastian.

Effects of pH Management During Selective Antegrade Cerebral Perfusion on Cerebral Microcirculation and Metabolism: Alpha-Stat Versus pH-Stat  Sebastian.
Total Arch Replacement Under Flow Monitoring During Selective Cerebral Perfusion Using a Single Pump  Hideyuki Shimizu, MD, PhD, Toru Matayoshi, CP, Masanori.

Total Arch Replacement Under Flow Monitoring During Selective Cerebral Perfusion Using a Single Pump  Hideyuki Shimizu, MD, PhD, Toru Matayoshi, CP, Masanori.
Circulatory Arrest and Low-Flow Cardiopulmonary Bypass Alter CREB Phosphorylation in Piglet Brain  Tatiana Zaitseva, PhD, Gregory Schears, MD, Steven.

Circulatory Arrest and Low-Flow Cardiopulmonary Bypass Alter CREB Phosphorylation in Piglet Brain  Tatiana Zaitseva, PhD, Gregory Schears, MD, Steven.
Unilateral Versus Bilateral Antegrade Cerebral Protection During Aortic Surgery: An Updated Meta-Analysis  Emiliano Angeloni, MD, Giovanni Melina, PhD,

Unilateral Versus Bilateral Antegrade Cerebral Protection During Aortic Surgery: An Updated Meta-Analysis  Emiliano Angeloni, MD, Giovanni Melina, PhD,
Newborn Aortic Arch Reconstruction With Descending Aortic Cannulation Improves Postoperative Renal Function  James M. Hammel, MD, Joseph J. Deptula, MPS,

Newborn Aortic Arch Reconstruction With Descending Aortic Cannulation Improves Postoperative Renal Function  James M. Hammel, MD, Joseph J. Deptula, MPS,
Response of Brain Oxygenation and Metabolism to Deep Hypothermic Circulatory Arrest in Newborn Piglets: Comparison of pH-Stat and Alpha-Stat Strategies 

Response of Brain Oxygenation and Metabolism to Deep Hypothermic Circulatory Arrest in Newborn Piglets: Comparison of pH-Stat and Alpha-Stat Strategies 
Comparison of neurologic outcome after deep hypothermic circulatory arrest with alpha- stat and pH-stat cardiopulmonary bypass in newborn pigs  Margaret.

Comparison of neurologic outcome after deep hypothermic circulatory arrest with alpha- stat and pH-stat cardiopulmonary bypass in newborn pigs  Margaret.
Susanne Lison, MD, Michael Spannagl, MD, PhD, Wulf Dietrich, MD, PhD 

Susanne Lison, MD, Michael Spannagl, MD, PhD, Wulf Dietrich, MD, PhD 
Xiumei Sun, MD, Jennifer Ellis, MD, Paul J. Corso, MD, Peter C

Xiumei Sun, MD, Jennifer Ellis, MD, Paul J. Corso, MD, Peter C

Similar presentations

Ads by Google