1. Therapeutic role of TR in HFD‐established diabetic mice
Therapeutic role of TR in HFD‐established diabetic mice ABody weights change of 6‐week‐old male wild‐type (WT) or Nlrp3−/− mice that were first fed with HFD for 14 weeks and then treated with different dose of oral TR for 6 weeks. n = 6 per group.B, CFed (B) or fasting (C) blood glucose concentrations at week 6 in the mice described in (A). n = 6.D–GITT (D, F) or GTT (E, G) performed at week 6 in the mice described in (A). n = 6 per group.Data information: Data are shown as mean and s.e.m. and are representative of two independent experiments. Statistics were analyzed using an unpaired Student's t‐test or two‐way ANOVA for (D–G): *P < 0.05, **P < 0.01, ***P < 0.001, NS, not significant.
Yi Huang et al. EMBO Mol Med. 2018;emmm
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