1. TR suppresses the assembly of NLRP3 inflammasome
TR suppresses the assembly of NLRP3 inflammasome Immunoblot analysis of ASC oligomerization in lysates of BMDMs treated with various doses (above lanes) of TR for 30 min and then stimulated with nigericin for another 30 min.Immunoprecipitation (IP) and immunoblot analysis of the interaction of endogenous NLRP3 and NEK7 in LPS‐primed BMDMs treated with various doses (above lanes) of TR for 30 min and then stimulated with nigericin for another 20 min.IP and immunoblot analysis of the interaction of endogenous NLRP3 and ASC in LPS‐primed BMDMs treated with various doses (above lanes) of TR for 30 min and then stimulated with nigericin for another 20 min.Data information: Data are representative of two or three independent experiments.Source data are available online for this figure.
Yi Huang et al. EMBO Mol Med. 2018;emmm
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