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Complete Resolution of Nonalcoholic Fatty Liver Disease After Bariatric Surgery: A Systematic Review and Meta-analysis  Yung Lee, Aristithes G. Doumouras,

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Presentation on theme: "Complete Resolution of Nonalcoholic Fatty Liver Disease After Bariatric Surgery: A Systematic Review and Meta-analysis  Yung Lee, Aristithes G. Doumouras,"— Presentation transcript:

1 Complete Resolution of Nonalcoholic Fatty Liver Disease After Bariatric Surgery: A Systematic Review and Meta-analysis  Yung Lee, Aristithes G. Doumouras, James Yu, Karanbir Brar, Laura Banfield, Scott Gmora, Mehran Anvari, Dennis Hong  Clinical Gastroenterology and Hepatology  Volume 17, Issue 6, Pages e11 (May 2019) DOI: /j.cgh Copyright © 2019 AGA Institute Terms and Conditions

2 Figure 1 Preferred Reporting Items for Systematic Reviews and Meta-Analyses diagram. Transparent reporting of systematic reviews and meta-analysis flow diagram outlining the search strategy results from initial search to included studies. Clinical Gastroenterology and Hepatology  , e11DOI: ( /j.cgh ) Copyright © 2019 AGA Institute Terms and Conditions

3 Figure 2 Proportion meta-analysis forest plot of biopsy-proven complete resolution of NAFLD features. (A) Steatosis, (B) inflammation/steatohepatitis, (C) ballooning degeneration, and (D) fibrosis. ES, effect size. Clinical Gastroenterology and Hepatology  , e11DOI: ( /j.cgh ) Copyright © 2019 AGA Institute Terms and Conditions

4 Figure 3 Random effects meta-analysis forest plot of NAS before and after surgery. IV, inverse variance; Sx, surgery. Clinical Gastroenterology and Hepatology  , e11DOI: ( /j.cgh ) Copyright © 2019 AGA Institute Terms and Conditions

5 Supplementary Figure 1 Proportion meta-analysis forest plot of histologic worsening of NAFLD (liver side effects) after surgery. ES, effect size. Clinical Gastroenterology and Hepatology  , e11DOI: ( /j.cgh ) Copyright © 2019 AGA Institute Terms and Conditions

6 Supplementary Figure 2 Subgroup analysis of biopsy-proven complete resolution of NAFLD features in patients who received RYGB. (A) Steatosis, (B) inflammation/steatohepatitis, (C) ballooning degeneration, and (D) fibrosis. ES, effect size. Clinical Gastroenterology and Hepatology  , e11DOI: ( /j.cgh ) Copyright © 2019 AGA Institute Terms and Conditions

7 Supplementary Figure 3 Subgroup analysis of histologic worsening of NAFLD (liver side effects) in patients who received RYGB. ES, effect size. Clinical Gastroenterology and Hepatology  , e11DOI: ( /j.cgh ) Copyright © 2019 AGA Institute Terms and Conditions

8 Supplementary Figure 4 Funnel plot assessing publication bias of complete resolution of steatosis (meta-analysis outcome with the most number of studies included). Clinical Gastroenterology and Hepatology  , e11DOI: ( /j.cgh ) Copyright © 2019 AGA Institute Terms and Conditions


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