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Bevacizumab Maintenance in Patients with Advanced Non–Small-Cell Lung Cancer, Clinical Patterns, and Outcomes in the Eastern Cooperative Oncology Group.

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Presentation on theme: "Bevacizumab Maintenance in Patients with Advanced Non–Small-Cell Lung Cancer, Clinical Patterns, and Outcomes in the Eastern Cooperative Oncology Group."— Presentation transcript:

1 Bevacizumab Maintenance in Patients with Advanced Non–Small-Cell Lung Cancer, Clinical Patterns, and Outcomes in the Eastern Cooperative Oncology Group Study: Results of An Exploratory Analysis  Ariel Lopez-Chavez, MD, MS, Todd Young, MD, Sophie Fages, MD, Larry Leon, MD, Joan H. Schiller, MD, Afshin Dowlati, MD, Julie R. Brahmer, MD, David H. Johnson, MD, Alan Sandler, MD, MS  Journal of Thoracic Oncology  Volume 7, Issue 11, Pages (November 2012) DOI: /JTO.0b013e318265b500 Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 ECOG 4599 patient disposition and analysis population. A, Analyzable patients: alive and without PD through six cycles + 21 days; (B, a total of 207 patients completed at least seven cycles of BV treatment. BV, bevacizumab; CP carboplatin + paclitaxel; PD, progressive disease. Journal of Thoracic Oncology 2012 7, DOI: ( /JTO.0b013e318265b500) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Kaplan–Meier estimates of (A) postinduction progression-free survival and (B) overall survival. Arrows indicate rates for patients at 1 year and at 2 years from the start of induction treatment (induction + postinduction periods). Numbers of patients at risk at designated time intervals are shown in this figure. Journal of Thoracic Oncology 2012 7, DOI: ( /JTO.0b013e318265b500) Copyright © 2012 International Association for the Study of Lung Cancer Terms and Conditions


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