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Relationship between Overall Survival and Response or Progression-Free Survival in Advanced Non–Small Cell Lung Cancer Patients Treated with Anti–PD-1/PD-L1.

Published byRatna Sudjarwadi Modified over 5 years ago

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Presentation on theme: "Relationship between Overall Survival and Response or Progression-Free Survival in Advanced Non–Small Cell Lung Cancer Patients Treated with Anti–PD-1/PD-L1."— Presentation transcript:

1 Relationship between Overall Survival and Response or Progression-Free Survival in Advanced Non–Small Cell Lung Cancer Patients Treated with Anti–PD-1/PD-L1 Antibodies  Takehito Shukuya, MD, PhD, Keita Mori, PhD, Joseph M. Amann, PhD, Erin M. Bertino, MD, Gregory A. Otterson, MD, Peter G. Shields, MD, Satoshi Morita, PhD, David P. Carbone, MD, PhD  Journal of Thoracic Oncology  Volume 11, Issue 11, Pages (November 2016) DOI: /j.jtho Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

2 Figure 1 The relationship between median overall survival and either median progression-free survival or response rate in prospective clinical trials using anti–programmed death protein 1/programmed death ligand 1 antibodies in 12 arms. Blue, nivolumab; pink, atezolizumab; brown, pembrolizumab; green, avelumab. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

3 Figure 2 The relationship between median overall survival and either median progression-free survival or response rate in prospective clinical trials using docetaxel monotherapy in 23 arms. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

4 Figure 3 (A)–(C) Kaplan–Meier curves of overall survival according to tumor response. (D) Kaplan-Meier curves of overall survival in patients who achieved and did not achieve 8-week progression-free status. (E) Kaplan–Meier curves of overall survival in patients who did and did not achieve 16-week progression-free status. (F) Kaplan–Meier curves of overall survival in patients who achieved and did not achieve 24-week progression-free status. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

5 Supplementary Figure 1 Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

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