1. Modular Sampling System Initiative Background and Status
2000 Spring Sponsor Meeting
Center for Process Analytical Chemistry

2. Background and Chronology of Activities
O&P Focus Group May 1999
Identified Sampling Systems as Area Of Interest
Sponsored Tutorial for Nov99 Sponsor Meeting
Tutorial Nov99 CPAC Meeting
Background/Reasons for Interest
Presentations by Suppliers/ End Users
Participation in IFPAC2000Meeting
Ad-hoc O&P Pittcon2000
Follow-up Meeting CPAC2000
What is Next?

3. O&P Focus Group Meeting May 99
Recognized Modular Sampling System Efforts in Semi Conductor Industry (Standard)
Vendors like Autoflow, A+, Swagelok etc. promoted modular designs
Recognized that current implementations of sample systems designs have not changed for many years
CPAC has promoted Versatile Micro Analytical Systems (VMAS) as a basis for future micro-analytical techniques
O&P decided to sponsor a SSISSS (Small Smart Integrated Sensor and Sampling System) Tutorial at CPAC Nov Meeting

4. Nov99 CPAC SSISSS Tutorial
ExxonMobil/DuPont Provided Introduction to Tutorial
Validation of Sample System Performance
Integration of Sensor with Sampling System
Four Suppliers of Sampling/Analyzer Systems Participated in Tutorial:
A+, Autoflow, Swagelok, Rosemount
Many components commercially Available
GCX example of self-contained miniaturized GC (GC on a pole)
Recognition
Modular Sampling System can be a platform to integrate VMAS
Bridge between Process Sample (Macro world) Micro Fluidics Sensors/Analyzers

5. Driving Forces for Change
Reduce Cost of Ownership
Non Recurring Costs = Cost to Build
Operating Cost
Data Validation (Fit for Use)

6. A P T F Integration of Sample System and Sensors
Mainly a Trust Configuration
Now a Trust & Verify Configuration A
Analyzer
Controller
Field LAN
Sample Conditioning System F T P
Process Stream
All System Components in Contact with Sample including the Sensors
All Additional Electronic and Computing Components Required to Generate Analytical Result
Level 0
Level 1

7. A P T F Level 0 Subsystem Integration Purpose:
Prepare and Verify a Representative Sample
(Compatible with Analyzer Sensor)
Integrated Sampling/Sensor System A
Sample Conditioning System F T P
Opportunity:
Packaging as an Integrated Sensor and Sampling System
Size
Cost
Process Stream
Issues:
Size
Standardization
VMAS
Level 0

8. A P T F Separation or Integration of Level 0/1 Subsystems Objective:
Analyzer
Controller
Field LAN F T P
Objective:
Close to Sample Tap
Process Stream
Integrated Sampling/Sensor System
Options:
Remote
Separate but Close
Integrated
Level 0
Level 1

9. $$ A P T F Integration of Level 0/1 Subsystems
Integrated Sampling/Sensor/Controller System A
Analyzer
Controller
Field LAN F T P
Process Stream $$
Level 0
Level 1

10. Nov99 CPAC SSISSS Tutorial
ExxonMobil/DuPont Provided Introduction to Tutorial
Validation of Sample System Performance
Integration of Sensor with Sampling System
Four Suppliers of Sampling/Analyzer Systems Participated in Tutorial:
A+, Autoflow, Swagelok, Rosemount
Many components commercially Available
GCX example of self-contained miniaturized GC (GC on a pole)
Recognition
Modular Sampling System can be a platform to integrate VMAS
Bridge between Process Sample (Macro world) Micro Fluidics Sensors/Analyzers

11. Nov99 CPAC SSISSS Tutorial (Vendor Presentations)
Swagelok
Autoflow A+
Rosemount

12. Nov99 CPAC SSISSS Tutorial
ExxonMobil/DuPont Provided Introduction to Tutorial
Validation of Sample System Performance
Integration of Sensor with Sampling System
Four Suppliers of Sampling/Analyzer Systems Participated in Tutorial:
A+, Autoflow, Swagelok, Rosemount
Many components commercially Available
GCX example of self-contained miniaturized GC (GC on a pole)
Recognition
Modular Sampling System can be a platform to integrate VMAS
Bridge between Process Sample (Macro world) and Micro Fluidics Sensors/Analyzers

13. IFPAC2000
ExxonMobil Presented Plenary Paper Promoting SSISSS
Sample System Infrastructure accounts for 50+% Cost to Build
Proposed Conceptual Design for SSISSS
Highlighted sensor and analyzer transmitter configurations
Sampling System Session
Presentations by A+, Autoflow, etc.
Sampling Systems enjoyed a High Profile
CPAC/ExxonMobil sponsored Workshop
Confirmed high interest in Modular Sampling System
Provided input for the ISA Standardization effort

14. For a major greenfield project
TODAY’S COST OF BUILD
For a major greenfield project

15. TODAY’S COST OF OWNERSHIP

16. IMAGINE THE FUTURE A P T F Field LAN Process Stream Level 0 Level 1
Analyzer
Controller T F
Level 0
Level 1

17. IMAGINE THE FUTURE P F T A Sensor = Moisture Probe Sensor/Signal Bus
FLAN (Optical Fiber) P F
IA Controller(ASIC) & Interface Module T A
Sensor/Signal Bus
Original Picture of Gas Delivery System courtesy Valin Corporation;

18. IMAGINE THE FUTURE
Sensor = RAMAN Probe P F T
Interface
Module A

19. Sensor = Moisture Probe
IMAGINE THE FUTURE
FLAN (Optical Fiber)
Sensor/Signal Bus IA
Controller
(ASIC) A T P F
Sensor = Moisture Probe

20. IMAGINE THE FUTURE
GCX Picture courtesy Rosemount Analytical

21. IFPAC2000
ExxonMobil Presented Plenary Paper Promoting SSISSS
Sample System Infrastructure accounts for 50+% Cost to Build
Proposed Conceptual Design fro SSISSS
Highlighted sensor and analyzer transmitter configurations
Sampling System Session
Presentations by A+, Autoflow, etc.
Sampling Systems enjoyed a High Profile
CPAC/ExxonMobil sponsored Workshop
Confirmed high interest in Modular Sampling System
Provided input for the ISA Standardization effort

22. IFPAC2000
ExxonMobil Presented Plenary Paper Promoting SSISSS
Sample System Infrastructure accounts for 50+% Cost to Build
Proposed Conceptual Design fro SSISSS
Highlighted sensor and analyzer transmitter configurations
Sampling System Session
Presentations by A+, Autoflow, etc.
Sampling Systems enjoyed a High Profile
CPAC/ExxonMobil sponsored Workshop
Confirmed high interest in Modular Sampling System
Provided input for the ISA Standardization effort

23. Pittcon2000 (New Orleans)
O&P Ad-Hoc Meeting of Sponsor End-users
DuPont, Dow, Dow-Corning, CPAC, Rohm&Haas, ExxonMobil
Main Goal: Identify Typical Sample System Designs as Candidates for Modular Design
Reviewed some typical gas/liquid sample System Designs
Rob DuBois Presented a Modular Component/Service Matrix
Discussed next steps
Present Sample System Data at May CPAC Meeting
Next Step is to Open Up Discussion (3rd parties)
Leverage ISA Meeting in New Orleans (Aug00)
Role of CPAC in Facilitating Development/Testing of a Prototype System
Larry Ricker/Lloyd Burgess to Present Proposal

24. Status CPAC Meeting May 1999 Done
O&P Identified Modular Sampling Systems
CPAC Meeting Nov Done
O&P Sponsored Tutorial
IFPAC2000 Meeting Done
Plenary Presentation Promoted SSISS
Session on Modular Sampling Systems
CPAC Sponsored Workshop
Pittcon Done
Ad-hoc O&P Meeting
Propose Candidate Sampling System Descriptions
CPAC Meeting May TBD

25. What is Next? CPAC Meeting May 2000 (Sampling Focus Group – Wednesday)
Review and Agree on Sample System Information Package
Involvement of 3rd parties
How do we distribute package (Distribution List, Meeting?)
Expectations for proposals from Suppliers (Paper designs?)
Joint Effort with ISA (Meeting in Aug, New Orleans)
Evaluation of Designs - Recommendation
Prototype design/manufacturing/testing at CPAC
Larry Ricker/Lloyd Burgess proposal
Program to Evaluate Test Platforms fro Micro Analytical Devices
CPAC Proposal – Lloyd Burgess

26. Acknowledgements Dow – Rob Dubois/Ron O’Reily/Brian Worthington
Dow Corning - Jim Tatera/Gary Bokerman
DuPont - Bob Bucher
Rohm&Haas – Joe Sung
Honeywell - Ken Creasy
Akzo Nobel – Foad Mozayeni
CPAC - Lloyd Burgess/Larry Ricker