1. Jennifer McVean, MD September 23, 2010
Type 1 Diabetes
Jennifer McVean, MD
September 23, 2010

2. Outline Type 1 diabetes: increasing incidence and prevalence
Exciting research and developments in type 1 diabetes
Juvenile Diabetes Research Foundation and The Walk to Cure Diabetes

3. Type 1 Diabetes Autoimmune Disease
White blood cells attack & destroy islet cells in pancreas which produce insulin
Absolute insulin deficiency
Symptoms: polyuria, polydipsia, weight loss
Requires lifelong treatment with insulin given by injection or subcutaneous infusion

4. Type 1 Diabetes One of the most common chronic diseases of childhood
In the US:
13,000 new childhood diagnoses per year
Prevalence for ages 0-19 years is:
1/300 – 1/500
Number of new patients annually has tripled in the past 20 years

6. T1D incidence is rising 3-5% per year
Incidence /100,000/ yr
in children aged 0-14
REWERS

7. Therapeutic Areas Immune Therapies Stop the Attack!
Beta Cell Therapies
Complications Therapies
Glucose Control
Stop the Attack!
Restore Beta Cells!
Prevent, Stop, Reduce!
Tight Control!

12. Omnipod tubeless CSII

13. Continuous Glucose Monitoring

14. Integrated CSII & CGMS

15. What’s ahead…

17. Mission: to find a cure for type 1 diabetes and its complications
JDRF
Mission: to find a cure for type 1 diabetes and its complications

18. Who is JDRF?
Founded in 1970 by parents of children with type 1 diabetes 
Raises money and advocates for government spending for type 1 diabetes research
Global leader in funding research toward a cure for type 1 diabetes
Sets the agenda for diabetes research worldwide 
Largest charitable funder of type 1 research

19. JDRF Has funded more than $1.4 billion in research
JDRF annually receives top rankings from organizations that rate charities
More than 80 percent of our expenditures directly support research and research-related education 19

20. Sunday, October 3 at Myrick Park 12pm Registration 1pm Walk