1. Up-regulation of p21-activated kinase 1 by in vitro treatment with interleukin 1-beta and its increased expression in ovarian endometriotic cysts 
Mi Young Lee, M.D., M.S., Sung Hoon Kim, M.D., Ph.D., Hyo Jin Ihm, M.S., Hee Dong Chae, M.D., Ph.D., Chung-Hoon Kim, M.D., Ph.D., Byung Moon Kang, M.D., Ph.D. 
Fertility and Sterility 
Volume 96, Issue 2, Pages (August 2011)
DOI: /j.fertnstert
Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

2. Figure 1
(A) Effects of TNF-α or IL-1β on the expression of Pak1 in Ishikawa cells. Western blot analysis of Ishikawa cells treated with either vehicle (C), TNF-α 10 ng/mL (T10), TNF-α 25 ng/mL (T25), IL-1β 10 ng/mL (IL10), or IL-1β 25 ng/mL (IL25) for 24 hours (a, b) and 48 hours (c, d), respectively. Results are expressed as percents, where cells treated with vehicle are normalized to 100%. (B) Effects of TNF-α or IL-1β on the expression of Pak1 in ESCs. Western blot analysis of ESCs treated with either vehicle (C), TNF-α 10 ng/mL (T10), TNF-α 25 ng/mL (T25), IL-1β 10 ng/mL (IL10), or IL-1β 25 ng/mL (IL25) for 24 hours (a, b) and 48 hours (c, d), respectively. Results are expressed as percents, where cells treated with vehicle are normalized to 100%. ∗P=.023 vs. vehicle; ∗∗P=.004 vs. vehicle, respectively. (C) Representative micrographs of Pak1 immunostaining in the normal endometrium during the midsecretory phase (a: ×200, b: ×400) and the ovarian endometriotic cyst during the secretory phase (c: ×200, d: ×400). (D) HSCOREs of Pak1 immunostaining in the glandular cells (a) and stromal cells (b) throughout the menstrual cycle. W = whole menstrual stages put together; P = proliferative phase; S = secretory phase. Each number in the bars indicates the number of samples recruited. Data of HSCOREs are expressed as mean ± SEM. ∗∗∗P<.001, ∗∗P<.005, ∗P<.05 vs. control, respectively.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions