1. Cystatin C levels and risk of death from all causes
Cystatin C level (mg/L)
Hazard ratio (adjusted) (95% CI)
Quintile 1 (<0.89)
1.00
Quintile 2 ( )
1.08 ( )
Quintile 3 ( )
1.23 ( )
Quintile 4 ( )
1.34 ( )
Quintile 5a ( )
1.77 ( )
Quintile 5b ( )
2.18 ( )
Quintile 5c (>1.60)
2.58 ( )
Shlipak MG et al. N Engl J Med 2005; 352:

2. Creatinine levels and risk of death from all causes
Creatinine level (values in men/women [mg/L])
Hazard ratio (adjusted)
(95% CI)
Quintile 1 (<0.85/0.65)
1.00
Quintile 2 ( / )
0.70 ( )
Quintile 3 ( / )
0.84 ( )
Quintile 4 ( / )
0.83 ( )
Quintile 5a ( / )
1.00 ( )
Quintile 5b ( / )
0.95 ( )
Quintile 5c (>1.56/1.16)
1.48 ( )
Shlipak MG et al. N Engl J Med 2005; 352:

3. Adjusted risk for CV death, MI, and stroke in highest (>1
Adjusted risk for CV death, MI, and stroke in highest (>1.29 mg/L) vs two lowest (< 0.99 mg/L) quintiles of cystatin C
End point
Hazard ratio (95% CI)
CV death
2.27 ( ) MI
1.48 ( )
Stroke
1.47 ( )
Shlipak MG et al. N Engl J Med 2005; 352: