1. Molecular Genetics Jeopardy
Vocab
DNA structure/
Replication
Transcription
Translation
Mutations
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Final Jeopardy

2. 1 - $100 What happens in transcription and translation?
Transcription: mRNA molecule made from DNA
Translation: amino acid sequence made from mRNA

3. 1 - $200
What enzyme adds nucleotides to a growing piece of DNA during DNA replication?
DNA polymerase

4. 1 - $300
What are the three types of RNA
mRNA, tRNA, rRNA

5. 1 - $400 What are introns and exons?
During mRNA processing, introns are cut out and exons stay in

6. 1 - $500
What is this called (circled) and what are each of the parts called
Nucleotide-made up of sugar, phosphate and nitrogenous base

7. 2 - $100 What are the bases that make up DNA? Which pair with which?
Adenine-thymine, cytosine-guanine

8. 2 - $200
What protein unwinds DNA during replication?
helicase

9. 2 - $300
If one strand of DNA reads: 3’ ATGCGTA 5’ what will the other strand read?
5’ TACGCAT 3’

10. 2 - $400
Why is DNA replication called semi-conservative?

11. 2 - $500 Label the parts of DNA replication. A-helicase
B-leading strand
C-lagging strand
D-DNA polymerase
E-5’
F-3’ B C D

12. 3 - $100
What is the product of transcription?
mRNA molecule

13. 3 - $200
If the DNA sequence of a gene begins with ATGCTG, what will the mRNA read after transcription?
UACGAC

14. 3 - $300 Where does transcription occur and why?
In the nucleus because DNA is in the nucleus

15. 3 - $400 What are three differences between DNA and RNA?
DNA is double stranded, has deoxyribose sugar, has T instead of U

16. 3 - $500 What happens during mRNA processing?
Introns spliced out, 5’ cap and poly A tail

17. 4 - $100
Where does translation occur?
ribosome

18. 4 - $200
What is this molecule called?
tRNA

19. 4 - $300 What are codons and anticodons?
Codons=3 base pairs of mRNA that code for an amino acid
anticodon-=complementary sequence on tRNA molecule

20. 4 - $400
If an mRNA sequence reads AUGGAU, what will the anti codons of the tRNA molecules that bind to the mRNA be?
UAC, CUA

21. 4 - $500
If an mRNA sequence reads AUG CCA GUG, what will the sequence of amino acids be after translation?
Met, pro, val

22. 5 - $100 What type of mutation is this? Normal: ACGAGG Mutated: CGAGG
Deletion, frameshift

23. 5 - $200 What type of mutation is this? Normal: AGTGTA
Mutated: AGTGATA
Insertion, frameshift

24. 5 - $300
Why is the difference between a frameshift and a substitution mutation?
A frameshift changes all amino acids after the mutation

25. 5 - $400
What is it called if a mutation leads to a codon changing to a stop codon?
nonsense

26. 5 - $500
What is the difference between missense, nonsense and silent mutations?
Missense-changes one amino acid
Nonsense-changes to a stop codon
Silent-doesn’t change amino acid

27. Final Jeopardy
Given the following template strand DNA sequence, what will the mRNA produced from transcription be? What will the amino acid sequence after translation be?
TACGGAACGCTG