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Mechanisms of arterial graft failure. II

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1 Mechanisms of arterial graft failure. II
Mechanisms of arterial graft failure. II. Chronic endothelial and smooth muscle cell proliferation in healing polytetrafluoroethylene prostheses  Alexander W. Clowes, M.D., Thomas R. Kirkman, B.A., Monika M. Clowes, B.A.  Journal of Vascular Surgery  Volume 3, Issue 6, Pages (June 1986) DOI: / (86) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

2 Fig. 1 Scanning electron micrographs demonstrate endothelium over graft (A) and adjacent artery (B) at 6 months (bar = 50 μm). Journal of Vascular Surgery 1986 3, DOI: ( / (86) ) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

3 Fig. 2 Scanning electron micrograph of endothelial growing edge (arrows) at 6 months (bar = 50 μm). Journal of Vascular Surgery 1986 3, DOI: ( / (86) ) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

4 Fig. 3 Light micrograph of en face autoradiographic preparation demonstrates two labeled endothelial cells (arrows) (bar = 100 μm). Journal of Vascular Surgery 1986 3, DOI: ( / (86) ) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

5 Fig. 4 Graph depicts distribution of sites of endothelial proliferation (thymidine indices) along graft. Note that although endothelial cells proliferate all along graft much of the proliferation is associated with the growing edges and the anastomoses. Journal of Vascular Surgery 1986 3, DOI: ( / (86) ) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

6 Fig. 5 Histologic cross-section of anastomosis at 12 months (bar = 1 μm). Journal of Vascular Surgery 1986 3, DOI: ( / (86) ) Copyright © 1986 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

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