1. SEPT12 deficiency causes sperm nucleus damage and developmental arrest of preimplantation embryos 
Ying-Hung Lin, Ph.D., Chuan-Kai Chou, M.Sc., Yu-Ching Hung, M.Sc., I-Shing Yu, Ph.D., Hsien-An Pan, M.D., Shu-Wha Lin, Ph.D., Pao-Lin Kuo, M.D. 
Fertility and Sterility 
Volume 95, Issue 1, Pages (January 2011)
DOI: /j.fertnstert
Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

2. Figure 1
Sperm nuclear DNA status of Septin12+/– chimeric mice and SEPT12 expression pattern during human spermiogenesis. (A) Spermatozoa were stained with AO (a), TB (b) and AB (c) dyes. (a) Spermatozoa with a normal (green) or abnormal nucleus (yellow). (b, c) Spermatozoa with a normal (light blue) or abnormal (blue) nucleus. (d-f) Spermatozoa isolated from the Septin 12+/-chimeric mice (n = 7) have an increased rate of nuclear DNA damage, compared with wild type (n = 3). ∗P < 0.05; ∗∗∗P < (B) SEPT12 signals during human spermiogenesis. SEPT12 (green), acrosome (red); nucleus (blue). The scale bar represents 5 μm.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions