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Gyun Jee Song, Ph.D., Vivian Lewis, M.D.  Fertility and Sterility 

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Presentation on theme: "Gyun Jee Song, Ph.D., Vivian Lewis, M.D.  Fertility and Sterility "— Presentation transcript:

1 Mitochondrial DNA integrity and copy number in sperm from infertile men 
Gyun Jee Song, Ph.D., Vivian Lewis, M.D.  Fertility and Sterility  Volume 90, Issue 6, Pages (December 2008) DOI: /j.fertnstert Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Long PCR products amplifying mitochondrial DNA from infertile men. The 8.7-kb band represents wild-type full-length mtDNA, and smaller bands represent deletions. Lane M: 1-kb DNA ladder (Bio-Rad, Hercules, CA); lanes 1-4: four representative PCR products after 30 cycles of amplification from four infertile men. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 Mitochondrial DNA (mtDNA) integrity (A) and copy number (B) in spermatozoa from infertile men. Normal: normal semen parameters (n = 24); Astheno: abnormal motility (n = 19); Oligo: oligozoospermia (n = 3); OATS: oligoasthenozoospermia (n = 11). ∗P<.05 from Tukey test. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions


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