1. ONLINE Histology Courseby
Robert W. Ogilvie & Roger H. Sawyer
Development, Resources & Student Participation
Online Demonstration of Course
…then, BIOL J530, Histology, a distributed learning course is the one for you! Histology is the Microscopic Architecture and Function of Cells, Tissues and Organs of an organism. This course, taught by Drs. Ogilvie and Sawyer, will present the structure and function of human cells, tissues and organs.
Cyberinfrastructure Symposium
2013

2. Structure-Function Units OF THE HUMAN BODY
What is Histology?
microscope view
osteon
alveolus
microscope view
nephron
microscope view
microscope view
smooth muscle
The microscopic architecture of the human body is designed so that each organ has structure-function units, i.e. structures designed to carry out the primary function of that organ. Three examples are: 1) the osteons of your bones without which you cannot stand up, 2) the alveoli of the lung without which you cannot breathe, 3) the nephron of the kidney without which you would not be able to rid your body of waste products and 4) the cardiac vascular unit without which your heart would stop beating. For each organ and component of the body you will learn these structure-function units so that as a either a health care provider or a lay person responsible for your health care you will be an informed patient, especially important in the age in which we live!!

3. Relevance of Histology to Professions
Physical Therapists
Physicians
Dentists
Nurses
Bioengineers
Knowledge of histology is relevant to many undergraduate and graduate programs. For example, physicians, dentists, nurses, physical therapists, bioengineers, anthropologists and archeologists. Histology is basic to all of the health sciences professions.
Archeologists
Public Health Professional

4. COURSE DEVELOPMENT 2008 Lecture/Laboratory Course 45 students
Standard Lecture – WebMic in Lab students
Online Lectures – WebMic in Lab students
Faculty Senate Approval
Initial Online Histology Course students
Fall Online Histology Course 53 students
Spring Online Histology Course 158 students
First Summer Offering (8 weeks) students
Fall Online Histology Course 160 students
Spring Online Histology Course 203 students
Epithelial Tissue
Knowledge of histology is relevant to many undergraduate and graduate programs. For example, physicians, dentists, nurses, physical therapists, bioengineers, anthropologists and archeologists. Histology is basic to all of the health sciences professions.
Connective tissue
Nervous Tissue
Muscle Tissue

5. COURSE resources Blended Course Online Course (Asynchronous)
WebMic (Virtual Microscope)
Dedicated Server (College IT)
Blackboard (University)
Computer Laboratories
(Department of Biology)
Online Course (Asynchronous)
WebMic (Virtual Microscope)
Biolucidea Cloud Server (NSF & College IT)
Biolucida Cloud Software (NSF & College IT)
Blackboard (University)
Distributed Learning (Office of Provost)
Knowledge of histology is relevant to many undergraduate and graduate programs. For example, physicians, dentists, nurses, physical therapists, bioengineers, anthropologists and archeologists. Histology is basic to all of the health sciences professions.
Published July 2005

6. Student participation
Medical University of South Carolina
Student participation
Glass Slide
Knowledge of histology is relevant to many undergraduate and graduate programs. For example, physicians, dentists, nurses, physical therapists, bioengineers, anthropologists and archeologists. Histology is basic to all of the health sciences professions.

7. Demographics over FOUR Semesters & Summer 2012
*12 SC State Students

8. EXAMPLE OF BLACKBOARD DATA
Fall Semester 2012 Course Activity

9. EXAMPLE OF BLACKBOARD DATA

10. Virtual Laboratories WebMic Virtual Slide
The virtual laboratories will utilize two virtual microscopy formats- WebMic with a Study Guide and Virtual Slides. WebMic is a Java programmed virtual microscope that will be used to learn the ABCs of histology and its use will be facilitated by a hard copy study guide. A collection of virtual slides will be used to assess your ability to correctly identify structures in specimens.
Virtual Slide

11. WebMic An interactive web accessible virtual microscope
Composed of nested static photomicrographs delivered by java applets
157 specimens comprehensively annotated to highlight important microscopic structures
Two self-assessment opportunities for students to assess their knowledge of microscopic structure.
WebMic is a web accessible virtual microscope containing more than 150 specimens. Students can call for structures to be labeled and quiz their knowledge with two forms of self assessment. Now, pause the presentation and then click the WebMic Start Page Image to view a demonstration video of WebMic created with Jing.

12. Virtual Slides
Virtual Slides created with Digital slide scanning technology has made it possible to convert a biological specimen on a glass slide completely into a digital format……..
So that microscopic architecture can be explored using..
…a computer….
…the Internet…..
…. specialized software!
You examine the specimen over the Internet just like you would using a microscope!
Digital slide scanning technology has made it possible now to convert a biological specimen on a glass slide completely to a digital format so that microscopic architecture can be explored using a computer and the Internet, with specialized software! You examine the specimen over the Internet just like you would using a microscope!

13. Virtual Slide Creation
Self-contained systems where the objective lens and the mechanism to move the slide or camera are enclosed.
Microscope equipped with a motorized stage, digital camera and computer software to control scanning and image collection.
MBFbioscience.com
Aperio.com

14. Digital Data in a Histological Slide
MBFbioscience.com

15. Advantages of Virtual Slides
Multiple levels of resolution are available from a virtual slide
Overview
0.08x
Entire 2”x3” inch slide scanned with a 20x objective (~300x absolute mag). It is not possible to see this large a field-of-view with a standard microscope.
Single section
0.63x
Even a single section overview
is impossible with a microscope
Anatomic detail 5x
Cellular detail
20x

16. USC Virtual Slide Collection (software currently in use)
mbfbioscience.com

17. BIOLUCIDA CLOUD Architectural and computing advances
Biolucida Technology
Efficient image streaming for 2D and 3D whole slide imagery.
Centralizes image storage with virtual copies for users.
Facilitates sharing of images for viewing and analysis.
Access to images and other functionality is permission-based.
Fully integrated with Stereo Investigator and Neurolucida.
Ram no longer a limit. Cloud (Server in lab, institution, or through MBF)
mbfbioscience.com

18. USC Biolucida Cloud (transitioning to use)
mbfbioscience.com

19. Blackboard Course Web Site