1. C3 Glomerulonephritis Associated With Complement Factor B Mutation
Sanjeev Sethi, MD, PhD, Richard J.H. Smith, MD, John J. Dillon, MD, Fernando C. Fervenza, MD, PhD 
American Journal of Kidney Diseases 
Volume 65, Issue 3, Pages (March 2015)
DOI: /j.ajkd
Copyright © 2015 National Kidney Foundation, Inc. Terms and Conditions

2. Figure 1
(A-C) Light microscopy shows membranoproliferative glomerulonephritis with increased mesangial cellularity, segmental endocapillary proliferation, double-contour formation along the capillary loops, and lobular accentuation of the glomerular tufts (A: Mason trichrome stain; original magnification, ×20; B: periodic acid–Schiff stain; original magnification, ×40; C: silver methenamine stain; original magnification, ×40). The interstitium was well preserved. Immunofluorescence microscopy (not shown) showed bright staining for C3 (3+), undetectable staining for immunoglobulin A (IgA) and IgM, and minimal staining for IgG (1+). (D) Electron microscopy showed mesangial and subendothelial deposits (black arrows; original magnification, ×4,800).
American Journal of Kidney Diseases  , DOI: ( /j.ajkd )
Copyright © 2015 National Kidney Foundation, Inc. Terms and Conditions