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Further Assessment to Determine the Additive Effect of Botulinum Toxin Type A on an Upper Extremity Exercise Program to Enhance Function Among Individuals.

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Presentation on theme: "Further Assessment to Determine the Additive Effect of Botulinum Toxin Type A on an Upper Extremity Exercise Program to Enhance Function Among Individuals."— Presentation transcript:

1 Further Assessment to Determine the Additive Effect of Botulinum Toxin Type A on an Upper Extremity Exercise Program to Enhance Function Among Individuals With Chronic Stroke but Extensor Capability  Steven L. Wolf, PhD, PT, S. Byron Milton, MD, Aimee Reiss, DPT, Kirk A. Easley, MS, Neeta V. Shenvi, PhD, Patricia C. Clark, PhD, RN  Archives of Physical Medicine and Rehabilitation  Volume 93, Issue 4, Pages (April 2012) DOI: /j.apmr Copyright © 2012 American Congress of Rehabilitation Medicine Terms and Conditions

2 Fig 1 CONSORT diagram of the progress through the phases (enrollment, intervention allocation, follow-up, and data analysis) of a parallel randomized trial of 2 groups (the BTX-A and a standardized exercise protocol, or saline injection and a standardized exercise protocol). Abbreviation: eval, evaluation. Archives of Physical Medicine and Rehabilitation  , DOI: ( /j.apmr ) Copyright © 2012 American Congress of Rehabilitation Medicine Terms and Conditions

3 Fig 2 Longitudinal changes (mean and 95% CI) in WMFT and FAS by treatment group (12 BTX-A patients and 13 control patients). A, C, and E for the WMFT: (A) Mean of the 15 timed tasks (seconds); (C) Six proximal joint timed tasks; (E) Number of the 6 proximal tasks not completed in 120 seconds. B, D, and F for the FAS: (B) Mean of the 15 tasks; (D) Mean score for the 6 proximal tasks; (F) Number of proximal tasks not completed (FAS 0, task not attempted with involved arm). Abbreviation: Eval, evaluation. Archives of Physical Medicine and Rehabilitation  , DOI: ( /j.apmr ) Copyright © 2012 American Congress of Rehabilitation Medicine Terms and Conditions

4 Fig 3 Longitudinal changes (mean and 95% CI) in wrist flexion AROM, MAS for the affected wrist musculature, and the normalized SIS scores for the hand function domain and the emotion domain by treatment group (12 BTX-A patients and 13 control patients). Time trend lines are the model-based means and 95% CIs. (A) Wrist flexion AROM (degrees). (B) Affected wrist MAS (1–6 ordinal score). (C) SIS hand function domain. (D) SIS emotion domain. Abbreviation: Eval, evaluation. Archives of Physical Medicine and Rehabilitation  , DOI: ( /j.apmr ) Copyright © 2012 American Congress of Rehabilitation Medicine Terms and Conditions


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