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Comparative Effectiveness of Platelet-Rich Plasma Injections for Treating Knee Joint Cartilage Degenerative Pathology: A Systematic Review and Meta-Analysis 

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Presentation on theme: "Comparative Effectiveness of Platelet-Rich Plasma Injections for Treating Knee Joint Cartilage Degenerative Pathology: A Systematic Review and Meta-Analysis "— Presentation transcript:

1 Comparative Effectiveness of Platelet-Rich Plasma Injections for Treating Knee Joint Cartilage Degenerative Pathology: A Systematic Review and Meta-Analysis  Ke-Vin Chang, MD, Chen-Yu Hung, MD, Fanny Aliwarga, MD, Tyng-Guey Wang, MD, Der-Sheng Han, MD, PhD, Wen-Shiang Chen, MD, PhD  Archives of Physical Medicine and Rehabilitation  Volume 95, Issue 3, Pages (March 2014) DOI: /j.apmr Copyright © 2014 American Congress of Rehabilitation Medicine Terms and Conditions

2 Fig 1 Flow diagram of the evaluation process for the inclusion or exclusion of studies. Archives of Physical Medicine and Rehabilitation  , DOI: ( /j.apmr ) Copyright © 2014 American Congress of Rehabilitation Medicine Terms and Conditions

3 Fig 2 Forest plot of the ES of functional changes from baseline at (A) 2 months, (B) 6 months, and (C) 12 months after PRP injections. Abbreviation: ES, effect sizes. Archives of Physical Medicine and Rehabilitation  , DOI: ( /j.apmr ) Copyright © 2014 American Congress of Rehabilitation Medicine Terms and Conditions

4 Fig 3 Forest plot of the ES of functional changes from baseline after HA injections. Abbreviation: ES, effect sizes. Archives of Physical Medicine and Rehabilitation  , DOI: ( /j.apmr ) Copyright © 2014 American Congress of Rehabilitation Medicine Terms and Conditions

5 Fig 4 Temporal relationships of effect sizes of functional changes after PRP, HA, and placebo injections. We also analyzed the treatment arm only comprising RCT of PRP interventions. Abbreviation: RCT, randomized controlled trials. Archives of Physical Medicine and Rehabilitation  , DOI: ( /j.apmr ) Copyright © 2014 American Congress of Rehabilitation Medicine Terms and Conditions

6 Fig 5 Funnel plots of the effective size of functional changes from baseline at (A) 2 months, (B) 6 months, and (C) 12 months after PRP injections. Archives of Physical Medicine and Rehabilitation  , DOI: ( /j.apmr ) Copyright © 2014 American Congress of Rehabilitation Medicine Terms and Conditions


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