1. The Hepatobiliary Paracellular Pathway: A Paradigm Revisited
James L. Boyer 
Gastroenterology 
Volume 147, Issue 5, Pages (November 2014)
DOI: /j.gastro
Copyright © Terms and Conditions

2. Figure 1
The left panel illustrates the anatomical location of claudins forming the zonula occludens between epithelial cells. The right panel (modified with permission from reference 8) illustrates the topology and secondary structure of claudin-2 with its 4 predicted membrane spanning domains and 2 extracellular loops (ECL1 and ECL2) extending into the paracellular space. The cation binding site is immediately to the right of the GLW signature in ECL1.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © Terms and Conditions