1. Figure 2 The depolarization theory of Brugada syndrome
Figure 2 | The depolarization theory of Brugada syndrome. Slow conduction in the right ventricular outflow tract (RVOT) might have a role in the development of the electrocardiographic and arrhythmic manifestations of Brugada syndrome. a | Right side of the heart. b | The action potential of the RVOT is delayed with respect to the action potential of the right ventricle (RV). Panels c and d show the current flowing from the RV to the RVOT and into the extracellular space during the hatched phase of the cardiac cycle. Panels e and f show a reversal of the potential gradients between RV and RVOT, with the current passing away from lead V2IC3. RA, right atrium. Reprinted from Meregalli, E. G. et al. Pathophysiological mechanisms of Brugada syndrome: depolarization disorder, repolarization disorder, or more? Cardiovasc. Res. 67, 367–378 (2005), with permission from Oxford University Press.
Reprinted from Meregalli, E. G. et al. Pathophysiological mechanisms of Brugada syndrome: depolarization disorder,
repolarization disorder, or more? Cardiovasc. Res. 67, 367–378 (2005), with permission from Oxford University Press
Sieira, J. et al. (2016) Pathogenesis and management of Brugada syndrome
Nat. Rev. Cardiol. doi: /nrcardio