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Felix Ratjen, Paul Koker, David E

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1 Tiotropium Respimat® in cystic fibrosis: Phase 3 and Pooled phase 2/3 randomized trials 
Felix Ratjen, Paul Koker, David E. Geller, Berengere Langellier-Cocteaux, Florence Le Maulf, Sabine Kattenbeck, Petra Moroni-Zentgraf, J. Stuart Elborn  Journal of Cystic Fibrosis  Volume 14, Issue 5, Pages (September 2015) DOI: /j.jcf Copyright © 2015 European Cystic Fibrosis Society. Terms and Conditions

2 Fig. 1 Adjusted mean FEV1 AUC0–4h (percent-predicted±SE) change from baseline by weeks (FAS). A. phase 3 trial; B. pooled phase 2 and 3 trials. AUC0–4h, area under the curve from 0 to 4h; FAS: full analysis set; FEV1: forced expiratory volume in 1s; SE: standard error. Journal of Cystic Fibrosis  , DOI: ( /j.jcf ) Copyright © 2015 European Cystic Fibrosis Society. Terms and Conditions


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