1. A randomized controlled trial of inhaled l-Arginine in patients with cystic fibrosis 
H. Grasemann, E. Tullis, F. Ratjen 
Journal of Cystic Fibrosis 
Volume 12, Issue 5, Pages (September 2013)
DOI: /j.jcf
Copyright © 2012 European Cystic Fibrosis Society. Terms and Conditions

2. Fig. 1
Changes in forced vital capacity (FVC) and forced expiratory volume in 1s (FEV1) after 14days of l-arginine or placebo inhalation. Data are expressed as % change from baseline % predicted.
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
Copyright © 2012 European Cystic Fibrosis Society. Terms and Conditions

3. Fig. 2
Changes in the fraction of exhaled nitric oxide (FENO) after 14days of l-arginine or placebo inhalation. Data are expressed as % from respective baseline. The increase in FENO after l-arginine was statistically significant (p=0.027, paired t-test).
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
Copyright © 2012 European Cystic Fibrosis Society. Terms and Conditions

4. Fig. 3
Sputum amino acids and ADMA concentrations before and after 14days of l-arginine or placebo inhalation. There was a significant increase in the concentrations of l-arginine, l-citrulline, l-ornithine and ADMA (pb0.05, respectively) after l-arginine but not placebo inhalation.
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
Copyright © 2012 European Cystic Fibrosis Society. Terms and Conditions